| Nomenclature |
|---|
| HGNC (Hugo) | HNRNPC 5035 |
| Cards |
|---|
| Entrez_Gene (NCBI) | HNRNPC 3183 heterogeneous nuclear ribonucleoprotein C |
| Aliases | C1; C2; HNRNP; HNRPC; |
| SNRPC |
| GeneCards (Weizmann) | HNRNPC |
| Ensembl hg19 (Hinxton) | ENSG00000092199 [Gene_View] |
| Ensembl hg38 (Hinxton) | ENSG00000092199 [Gene_View] ENSG00000092199 [Sequence] chr14:21209136-21269479 [Contig_View] HNRNPC [Vega] |
| ICGC DataPortal | ENSG00000092199 |
| TCGA cBioPortal | HNRNPC |
| AceView (NCBI) | HNRNPC |
| Genatlas (Paris) | HNRNPC |
| WikiGenes | 3183 |
| SOURCE (Princeton) | HNRNPC |
| Genetics Home Reference (NIH) | HNRNPC |
| Genomic and cartography |
|---|
| GoldenPath hg38 (UCSC) | HNRNPC - chr14:21209136-21269479 - 14q11.2 [Description] (hg38-Dec_2013) |
| GoldenPath hg19 (UCSC) | HNRNPC - 14q11.2 [Description] (hg19-Feb_2009) |
| GoldenPath | HNRNPC - 14q11.2 [CytoView hg19] HNRNPC - 14q11.2 [CytoView hg38] |
| ImmunoBase | ENSG00000092199 |
| Mapping of homologs : NCBI | HNRNPC [Mapview hg19] HNRNPC [Mapview hg38] |
| OMIM | 164020 |
| Gene and transcription |
|---|
| Genbank (Entrez) | AB209527 AK126950 AK223517 AK225032 AK292619 |
| RefSeq transcript (Entrez) | NM_001077442 NM_001077443 NM_004500 NM_031314 |
| RefSeq genomic (Entrez) | |
| Consensus coding sequences : CCDS (NCBI) | HNRNPC |
| Cluster EST : Unigene | Hs.675546 [ NCBI ] |
| CGAP (NCI) | Hs.675546 |
| Alternative Splicing Gallery | ENSG00000092199 |
| Gene Expression | HNRNPC [ NCBI-GEO ] HNRNPC [ EBI - ARRAY_EXPRESS ]
HNRNPC [ SEEK ] HNRNPC [ MEM ] |
| Gene Expression Viewer (FireBrowse) | HNRNPC [ Firebrowse - Broad ] |
| SOURCE (Princeton) | Expression in : [Datasets] [Normal Tissue Atlas] [carcinoma Classsification] [NCI60] |
| Genevestigator | Expression in : [tissues] [cell-lines] [cancer] [perturbations] |
| BioGPS (Tissue expression) | 3183 |
| GTEX Portal (Tissue expression) | HNRNPC |
| Human Protein Atlas | ENSG00000092199-HNRNPC [pathology] [cell] [tissue] |
| Protein : pattern, domain, 3D structure |
|---|
| UniProt/SwissProt | P07910 [function] [subcellular_location] [family_and_domains] [pathology_and_biotech] [ptm_processing] [expression] [interaction] |
| NextProt | P07910 [Sequence] [Exons] [Medical] [Publications] |
| With graphics : InterPro | P07910 |
| Splice isoforms : SwissVar | P07910 |
| PhosPhoSitePlus | P07910 |
| Domaine pattern : Prosite (Expaxy) | RRM (PS50102) |
| Domains : Interpro (EBI) | hnRNP_C Nucleotide-bd_a/b_plait_sf RBD_domain_sf RRM_dom |
| Domain families : Pfam (Sanger) | RRM_1 (PF00076) |
| Domain families : Pfam (NCBI) | pfam00076 |
| Domain families : Smart (EMBL) | RRM (SM00360) |
| Conserved Domain (NCBI) | HNRNPC |
| DMDM Disease mutations | 3183 |
| Blocks (Seattle) | HNRNPC |
| PDB (RSDB) | 1TXP 1WF2 2MXY 2MZ1 3LN4 |
| PDB Europe | 1TXP 1WF2 2MXY 2MZ1 3LN4 |
| PDB (PDBSum) | 1TXP 1WF2 2MXY 2MZ1 3LN4 |
| PDB (IMB) | 1TXP 1WF2 2MXY 2MZ1 3LN4 |
| Structural Biology KnowledgeBase | 1TXP 1WF2 2MXY 2MZ1 3LN4 |
| SCOP (Structural Classification of Proteins) | 1TXP 1WF2 2MXY 2MZ1 3LN4 |
| CATH (Classification of proteins structures) | 1TXP 1WF2 2MXY 2MZ1 3LN4 |
| Superfamily | P07910 |
| Human Protein Atlas [tissue] | ENSG00000092199-HNRNPC [tissue] |
| Peptide Atlas | P07910 |
| HPRD | 01243 |
| IPI | IPI00477313 IPI00216592 IPI00759822 IPI00759596 IPI01013087 IPI00910666 IPI00911096 IPI00877664 IPI00909232 IPI01026359 IPI01024875 IPI01025611 IPI01024858 IPI01026090 IPI01026329 IPI01026469 IPI01026471 IPI01024718 IPI01025103 IPI01025235 IPI00910718 IPI00868835 |
| Protein Interaction databases |
|---|
| DIP (DOE-UCLA) | P07910 |
| IntAct (EBI) | P07910 |
| FunCoup | ENSG00000092199 |
| BioGRID | HNRNPC |
| STRING (EMBL) | HNRNPC |
| ZODIAC | HNRNPC |
| Ontologies - Pathways |
|---|
| QuickGO | P07910 |
| Ontology : AmiGO | mRNA splicing, via spliceosome mRNA splicing, via spliceosome mRNA splicing, via spliceosome nuclear chromatin RNA polymerase II proximal promoter sequence-specific DNA binding RNA polymerase II distal enhancer sequence-specific DNA binding osteoblast differentiation RNA binding RNA binding RNA binding RNA binding mRNA 3'-UTR binding protein binding extracellular region nucleus nucleus nucleus nucleoplasm nucleoplasm spliceosomal complex telomerase holoenzyme complex cytosol poly(U) RNA binding RNA splicing actin cytoskeleton membrane RNA metabolic process nucleosomal DNA binding negative regulation of telomere maintenance via telomerase protein-containing complex protein-containing complex identical protein binding ATP-dependent chromatin remodeling telomerase RNA binding extracellular exosome 3'-UTR-mediated mRNA stabilization catalytic step 2 spliceosome N6-methyladenosine-containing RNA binding |
| Ontology : EGO-EBI | mRNA splicing, via spliceosome mRNA splicing, via spliceosome mRNA splicing, via spliceosome nuclear chromatin RNA polymerase II proximal promoter sequence-specific DNA binding RNA polymerase II distal enhancer sequence-specific DNA binding osteoblast differentiation RNA binding RNA binding RNA binding RNA binding mRNA 3'-UTR binding protein binding extracellular region nucleus nucleus nucleus nucleoplasm nucleoplasm spliceosomal complex telomerase holoenzyme complex cytosol poly(U) RNA binding RNA splicing actin cytoskeleton membrane RNA metabolic process nucleosomal DNA binding negative regulation of telomere maintenance via telomerase protein-containing complex protein-containing complex identical protein binding ATP-dependent chromatin remodeling telomerase RNA binding extracellular exosome 3'-UTR-mediated mRNA stabilization catalytic step 2 spliceosome N6-methyladenosine-containing RNA binding |
| Pathways : KEGG | Spliceosome |
| NDEx Network | HNRNPC |
| Atlas of Cancer Signalling Network | HNRNPC |
| Wikipedia pathways | HNRNPC |
| Orthology - Evolution |
|---|
| OrthoDB | 3183 |
| GeneTree (enSembl) | ENSG00000092199 |
| Phylogenetic Trees/Animal Genes : TreeFam | HNRNPC |
| HOGENOM | P07910 |
| Homologs : HomoloGene | HNRNPC |
| Homology/Alignments : Family Browser (UCSC) | HNRNPC |
| Gene fusions - Rearrangements |
|---|
| Fusion : Mitelman | HNRNPC/ZNF219 [14q11.2/14q11.2] |
| Fusion : Mitelman | ZNF219/HNRNPC [14q11.2/14q11.2] [t(14;14)(q11;q11)] |
| Fusion : Quiver | HNRNPC |
| Polymorphisms : SNP and Copy number variants |
|---|
| NCBI Variation Viewer | HNRNPC [hg38] |
| dbSNP Single Nucleotide Polymorphism (NCBI) | HNRNPC |
| dbVar | HNRNPC |
| ClinVar | HNRNPC |
| 1000_Genomes | HNRNPC |
| Exome Variant Server | HNRNPC |
| ExAC (Exome Aggregation Consortium) | ENSG00000092199 |
| GNOMAD Browser | ENSG00000092199 |
| Varsome Browser | HNRNPC |
| Genetic variants : HAPMAP | 3183 |
| Genomic Variants (DGV) | HNRNPC [DGVbeta] |
| DECIPHER | HNRNPC [patients] [syndromes] [variants] [genes] |
| CONAN: Copy Number Analysis | HNRNPC |
| Mutations |
|---|
| ICGC Data Portal | HNRNPC |
| TCGA Data Portal | HNRNPC |
| Broad Tumor Portal | HNRNPC |
| OASIS Portal | HNRNPC [ Somatic mutations - Copy number] |
| Somatic Mutations in Cancer : COSMIC | HNRNPC [overview] [genome browser] [tissue] [distribution] |
| Somatic Mutations in Cancer : COSMIC3D | HNRNPC |
| Mutations and Diseases : HGMD | HNRNPC |
| LOVD (Leiden Open Variation Database) | Whole genome datasets |
| LOVD (Leiden Open Variation Database) | LOVD - Leiden Open Variation Database |
| LOVD (Leiden Open Variation Database) | LOVD 3.0 shared installation |
| BioMuta | search HNRNPC |
| DgiDB (Drug Gene Interaction Database) | HNRNPC |
| DoCM (Curated mutations) | HNRNPC (select the gene name) |
| CIViC (Clinical Interpretations of Variants in Cancer) | HNRNPC (select a term) |
| intoGen | HNRNPC |
| Cancer3D | HNRNPC(select the gene name) |
| Impact of mutations | [PolyPhen2] [Provean] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser] |
| Diseases |
|---|
| OMIM | 164020 |
| Orphanet | |
| DisGeNET | HNRNPC |
| Medgen | HNRNPC |
| Genetic Testing Registry | HNRNPC
|
| NextProt | P07910 [Medical] |
| TSGene | 3183 |
| GENETests | HNRNPC |
| Target Validation | HNRNPC |
| Huge Navigator |
HNRNPC [HugePedia] |
| snp3D : Map Gene to Disease | 3183 |
| BioCentury BCIQ | HNRNPC |
| ClinGen | HNRNPC |
| Clinical trials, drugs, therapy |
|---|
| Chemical/Protein Interactions : CTD | 3183 |
| Chemical/Pharm GKB Gene | PA162391217 |
| Clinical trial | HNRNPC |
| Miscellaneous |
|---|
| canSAR (ICR) | HNRNPC (select the gene name) |
| DataMed Index | HNRNPC |
| Probes |
|---|
| Litterature |
|---|
| PubMed | 210 Pubmed reference(s) in Entrez |
| GeneRIFs | Gene References Into Functions (Entrez) |
| CoreMine | HNRNPC |
| EVEX | HNRNPC |
| GoPubMed | HNRNPC |
| iHOP | HNRNPC |
