HNRNPR (heterogeneous nuclear ribonucleoprotein R)

2003-06-01  

Identity

HGNC
HNRNPR
LOCATION
1p36.12
LOCUSID
10236
ALIAS
HNRPR,hnRNP-R
FUSION GENES
Show Gene Fusions

Other Information

Locus ID:

NCBI: 10236
MIM: 607201
HGNC: 5047
Ensembl: ENSG00000125944

Variants:

dbSNP: 10236
ClinVar: 10236
TCGA: ENSG00000125944
COSMIC: HNRNPR

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000125944ENST00000302271O43390
ENSG00000125944ENST00000374612O43390
ENSG00000125944ENST00000374616O43390
ENSG00000125944ENST00000427764O43390
ENSG00000125944ENST00000478691O43390
ENSG00000125944ENST00000606561B4DT28
ENSG00000125944ENST00000641107A0A286YEZ8

Expression (GTEx)

0
10
20
30
40
50
60
70
Adipose - Subcutaneous
Adipose - Visceral
Adrenal Gland
Artery - Aorta
Artery - Tibial
Bladder
Brain - Amygdala
Brain - Anterior cingulate cortex
Brain - Caudate
Brain - Cerebellar Hemisphere
Brain - Cerebellum
Brain - Cortex
Brain - Frontal Cortex
Brain - Hippocampus
Brain - Hypothalamus
Brain - Nucleus accumbens
Brain - Putamen
Brain - Spinal cord
Brain - Substantia nigra
Breast - Mammary Tissue
Cells - Cultured fibroblasts
Cells - EBV - transformed lymphocytes
Cervix - Ectocervix
Cervix - Endocervix
Colon - Sigmoid
Colon - Transverse
Esophagus - Gastroesophageal Junction
Esophagus - Mucosa
Esophagus - Muscularis
Fallopian Tube
Heart - Atrial Appendage
Heart - Left Ventricle
Kidney - Cortex
Kidney - Medulla
Liver
Lung
Minor Salivary Gland
Muscle - Skeletal
Nerve - Tibial
Ovary
Pancreas
Pituitary
Prostate
Skin - Not Sun Exposed
Skin - Sun Exposed
Small Intestine - Terminal Ileum
Spleen
Stomach
Testis
Thyroid
Uterus
Vagina
Whole Blood

Pathways

PathwaySourceExternal ID
Gene ExpressionREACTOMER-HSA-74160
Processing of Capped Intron-Containing Pre-mRNAREACTOMER-HSA-72203
mRNA SplicingREACTOMER-HSA-72172
mRNA Splicing - Major PathwayREACTOMER-HSA-72163

Protein levels (Protein atlas)

Not detected
Low
Medium
High
cerebral cortex
cerebellum
hippocampus
caudate
thyroid gland
parathyroid gland
adrenal gland
nasopharynx
bronchus
lung
oral mucosa
salivary gland
esophagus
stomach 1
stomach 2
duodenum
small intestine
colon
rectum
liver
gallbladder
pancreas
kidney
urinary bladder
testis
epididymis
seminal vesicle
prostate
vagina
ovary
fallopian tube
endometrium 1
endometrium 2
cervix, uterine
placenta
breast
heart muscle
smooth muscle
skeletal muscle
soft tissue 1
soft tissue 2
adipose tissue
skin 1
skin 2
appendix
spleen
lymph node
tonsil
bone marrow

References

Pubmed IDYearTitleCitations
253380972014Presynaptic localization of Smn and hnRNP R in axon terminals of embryonic and postnatal mouse motoneurons.27
176729182007Violating the splicing rules: TG dinucleotides function as alternative 3' splice sites in U2-dependent introns.17
198086712009Identification of a heterogeneous nuclear ribonucleoprotein-recognition region in the HIV Rev protein.17
195812952009Heterogeneous nuclear ribonucleoprotein R enhances transcription from the naturally configured c-fos promoter in vitro.12
271947852016HNRNPR Regulates the Expression of Classical and Nonclassical MHC Class I Proteins.11
307552802019Heterogeneous nuclear ribonucleoproteins R and Q accumulate in pathological inclusions in FTLD-FUS.2
310799002019HNRNPR Variants that Impair Homeobox Gene Expression Drive Developmental Disorders in Humans.2
199020702009Changed profile of splicing regulator genes expression in response to exercise.1

Citation

Dessen P

HNRNPR (heterogeneous nuclear ribonucleoprotein R)

Atlas Genet Cytogenet Oncol Haematol. 2003-06-01

Online version: http://atlasgeneticsoncology.org/gene/40842/hnrnpr