HORMAD2 (HORMA domain containing 2)

2013-06-01  

Identity

HGNC
HORMAD2
LOCATION
22q12.2
LOCUSID
150280
ALIAS
CT46.2

Other Information

Locus ID:

NCBI: 150280
MIM: 618842
HGNC: 28383
Ensembl: ENSG00000176635

Variants:

dbSNP: 150280
ClinVar: 150280
TCGA: ENSG00000176635
COSMIC: HORMAD2

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000176635ENST00000336726Q8N7B1
ENSG00000176635ENST00000403975Q8N7B1
ENSG00000176635ENST00000450612F8WES9

Expression (GTEx)

0
5
10
15
20
25
30
35
40
45
Adipose - Subcutaneous
Adipose - Visceral
Adrenal Gland
Artery - Aorta
Artery - Tibial
Bladder
Brain - Amygdala
Brain - Anterior cingulate cortex
Brain - Caudate
Brain - Cerebellar Hemisphere
Brain - Cerebellum
Brain - Cortex
Brain - Frontal Cortex
Brain - Hippocampus
Brain - Hypothalamus
Brain - Nucleus accumbens
Brain - Putamen
Brain - Spinal cord
Brain - Substantia nigra
Breast - Mammary Tissue
Cells - Cultured fibroblasts
Cells - EBV - transformed lymphocytes
Cervix - Ectocervix
Cervix - Endocervix
Colon - Sigmoid
Colon - Transverse
Esophagus - Gastroesophageal Junction
Esophagus - Mucosa
Esophagus - Muscularis
Fallopian Tube
Heart - Atrial Appendage
Heart - Left Ventricle
Kidney - Cortex
Kidney - Medulla
Liver
Lung
Minor Salivary Gland
Muscle - Skeletal
Nerve - Tibial
Ovary
Pancreas
Pituitary
Prostate
Skin - Not Sun Exposed
Skin - Sun Exposed
Small Intestine - Terminal Ileum
Spleen
Stomach
Testis
Thyroid
Uterus
Vagina
Whole Blood

Protein levels (Protein atlas)

Not detected
Low
Medium
High
cerebral cortex
cerebellum
hippocampus
caudate
thyroid gland
parathyroid gland
adrenal gland
nasopharynx
bronchus
lung
oral mucosa
salivary gland
esophagus
stomach 1
stomach 2
duodenum
small intestine
colon
rectum
liver
gallbladder
pancreas
kidney
urinary bladder
testis
epididymis
seminal vesicle
prostate
vagina
ovary
fallopian tube
endometrium 1
endometrium 2
cervix, uterine
placenta
breast
heart muscle
smooth muscle
skeletal muscle
soft tissue 1
soft tissue 2
adipose tissue
skin 1
skin 2
appendix
spleen
lymph node
tonsil

References

Pubmed IDYearTitleCitations
228936172012HORMAD2/CT46.2, a novel cancer/testis gene, is ectopically expressed in lung cancer tissues.15
204736882010Association between genome-wide association studies reported SNPs and pediatric-onset Crohn's disease in Canadian children.6
279411312017Genome-wide association study identifies variants in HORMAD2 associated with tonsillectomy.6
300399142018HORMAD2 methylation-mediated epigenetic regulation of gene expression in thyroid cancer.3
247973352014Association of polymorphisms at HORMAD2 and prognosis in advanced non-small-cell lung cancer patients.2
248034222014Genetic study of Hormad1 and Hormad2 with non-obstructive azoospermia patients in the male Chinese population.1

Citation

Dessen P

HORMAD2 (HORMA domain containing 2)

Atlas Genet Cytogenet Oncol Haematol. 2013-06-01

Online version: http://atlasgeneticsoncology.org/gene/53337/hormad2