HOXA5 (homeobox A5)

2003-02-01  

Identity

HGNC
LOCATION
7p15.2
LOCUSID
ALIAS
HOX1,HOX1.3,HOX1C

Other Information

Locus ID:

NCBI: 3202
MIM: 142952
HGNC: 5106
Ensembl: ENSG00000106004

Variants:

dbSNP: 3202
ClinVar: 3202
TCGA: ENSG00000106004
COSMIC: HOXA5

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000106004ENST00000222726P20719

Expression (GTEx)

0
50
100
150

References

Pubmed IDYearTitleCitations
179570282008Regulation of angiogenesis through a microRNA (miR-130a) that down-regulates antiangiogenic homeobox genes GAX and HOXA5.164
228768402012MicroRNA-196a promotes non-small cell lung cancer cell proliferation and invasion through targeting HOXA5.66
266783412015HOXA5 Counteracts Stem Cell Traits by Inhibiting Wnt Signaling in Colorectal Cancer.54
163795942005A role for Hox A5 in regulating angiogenesis and vascular patterning.50
177855562007Inactivation of HOXA genes by hypermethylation in myeloid and lymphoid malignancy is frequent and associated with poor prognosis.48
147017622004HOXA5-induced apoptosis in breast cancer cells is mediated by caspases 2 and 8.38
155452682005HOXA5-twist interaction alters p53 homeostasis in breast cancer cells.31
178047112007HOXA5 acts directly downstream of retinoic acid receptor beta and contributes to retinoic acid-induced apoptosis and growth inhibition.24
157579032005Identification of transcriptional targets of HOXA5.23
271576142016HOXA5 determines cell fate transition and impedes tumor initiation and progression in breast cancer through regulation of E-cadherin and CD24.21

Citation

Dessen P

HOXA5 (homeobox A5)

Atlas Genet Cytogenet Oncol Haematol. 2003-02-01

Online version: http://atlasgeneticsoncology.org/gene/40849/hoxa5