HOXC10 (homeobox C10)

2007-12-01  

Identity

HGNC
LOCATION
12q13.13
LOCUSID
ALIAS
HOX3I
FUSION GENES

Other Information

Locus ID:

NCBI: 3226
MIM: 605560
HGNC: 5122
Ensembl: ENSG00000180818

Variants:

dbSNP: 3226
ClinVar: 3226
TCGA: ENSG00000180818
COSMIC: HOXC10

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000180818ENST00000303460Q9NYD6
ENSG00000180818ENST00000303460Q53XI4
ENSG00000180818ENST00000515593D6RAG4

Expression (GTEx)

0
10
20
30
40
50
60
70
80
90
100

Protein levels (Protein atlas)

Not detected
Low
Medium
High

References

Pubmed IDYearTitleCitations
179749572007Gene expression analysis of preinvasive and invasive cervical squamous cell carcinomas identifies HOXC10 as a key mediator of invasion.81
128534862003Early mitotic degradation of the homeoprotein HOXC10 is potentially linked to cell cycle progression.34
246706852014Epigenetic reprogramming of HOXC10 in endocrine-resistant breast cancer.24
266479002016Fat depot-specific expression of HOXC9 and HOXC10 may contribute to adverse fat distribution and related metabolic traits.13
262792642015HOXC10 up-regulation contributes to human thyroid cancer and indicates poor survival outcome.11
304298912018Overexpression of HOXC10 promotes angiogenesis in human glioma via interaction with PRMT5 and upregulation of VEGFA expression.11
296768492018HOXC10 promotes proliferation and invasion and induces immunosuppressive gene expression in glioma.7
286568832017MiR-136 inhibits gastric cancer-specific peritoneal metastasis by targeting HOXC10.5
284749982017Homeodomain-containing gene 10 inhibits cell apoptosis and promotes cell invasion and migration in osteosarcoma cell lines.3
286052232018Homeobox C10 inhibits the osteogenic differentiation potential of mesenchymal stem cells.3

Citation

Dessen P

HOXC10 (homeobox C10)

Atlas Genet Cytogenet Oncol Haematol. 2007-12-01

Online version: http://atlasgeneticsoncology.org/gene/49868/hoxc10