Identity
HGNC
LOCATION
2q31.1
LOCUSID
ALIAS
HOX4,HOX4D,HOX4E,Hox-4.4
FUSION GENES
Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 3236
MIM: 142984
HGNC: 5133
Ensembl: ENSG00000128710
Variants:
dbSNP: 3236
ClinVar: 3236
TCGA: ENSG00000128710
COSMIC: HOXD10
RNA/Proteins
| Gene ID | Transcript ID | Uniprot |
|---|---|---|
| ENSG00000128710 | ENST00000249501 | P28358 |
Expression (GTEx)
Pathways
| Pathway | Source | External ID |
|---|---|---|
| Proteoglycans in cancer | KEGG | hsa05205 |
| Proteoglycans in cancer | KEGG | ko05205 |
| MicroRNAs in cancer | KEGG | hsa05206 |
| MicroRNAs in cancer | KEGG | ko05206 |
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 38829908 | 2024 | Joint-specific regulation of homeobox D10 expression in rheumatoid arthritis fibroblast-like synoviocytes. | 0 |
| 38829908 | 2024 | Joint-specific regulation of homeobox D10 expression in rheumatoid arthritis fibroblast-like synoviocytes. | 0 |
| 34825321 | 2022 | Upregulation of homeobox D10 expression suppresses invasion and migration of clear cell renal cell carcinoma through targeting of E-cadherin. | 1 |
| 35964231 | 2022 | Circ_0077109 sponges miR-139-5p and upregulates HOXD10 in trophoblast cells as potential mechanism for preeclampsia progression. | 2 |
| 34825321 | 2022 | Upregulation of homeobox D10 expression suppresses invasion and migration of clear cell renal cell carcinoma through targeting of E-cadherin. | 1 |
| 35964231 | 2022 | Circ_0077109 sponges miR-139-5p and upregulates HOXD10 in trophoblast cells as potential mechanism for preeclampsia progression. | 2 |
| 34292663 | 2021 | Circ_0000317/microRNA-520g/HOXD10 axis affects the biological characteristics of colorectal cancer. | 2 |
| 34292663 | 2021 | Circ_0000317/microRNA-520g/HOXD10 axis affects the biological characteristics of colorectal cancer. | 2 |
| 30552679 | 2019 | Gene expression signatures for HOXA4, HOXA9, and HOXD10 reveal alterations in transcriptional regulatory networks in colon cancer. | 7 |
| 30683109 | 2019 | Epigenetic inactivation of HOXD10 is associated with human colon cancer via inhibiting the RHOC/AKT/MAPK signaling pathway. | 19 |
| 30938888 | 2019 | Homeobox D10, a tumor suppressor, inhibits the proliferation and migration of esophageal squamous cell carcinoma. | 7 |
| 31106881 | 2019 | Downregulation of microRNA-92b-3p suppresses proliferation, migration, and invasion of gastric cancer SGC-7901 cells by targeting Homeobox D10. | 19 |
| 30552679 | 2019 | Gene expression signatures for HOXA4, HOXA9, and HOXD10 reveal alterations in transcriptional regulatory networks in colon cancer. | 7 |
| 30683109 | 2019 | Epigenetic inactivation of HOXD10 is associated with human colon cancer via inhibiting the RHOC/AKT/MAPK signaling pathway. | 19 |
| 30938888 | 2019 | Homeobox D10, a tumor suppressor, inhibits the proliferation and migration of esophageal squamous cell carcinoma. | 7 |
Citation
Dessen P
HOXD10 (homeobox D10)
Atlas Genet Cytogenet Oncol Haematol. 2011-09-01
Online version: http://atlasgeneticsoncology.org/gene/52373/hoxd10
