HP1BP3 (heterochromatin protein 1 binding protein 3)

2015-08-01  

Identity

HGNC
LOCATION
1p36.12
LOCUSID
ALIAS
HP1-BP74,HP1BP74
FUSION GENES

Other Information

Locus ID:

NCBI: 50809
MIM: 616072
HGNC: 24973
Ensembl: ENSG00000127483

Variants:

dbSNP: 50809
ClinVar: 50809
TCGA: ENSG00000127483
COSMIC: HP1BP3

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000127483ENST00000312239Q5SSJ5
ENSG00000127483ENST00000375000Q5SSJ5
ENSG00000127483ENST00000375003Q5SSJ5
ENSG00000127483ENST00000414993B0QZK9
ENSG00000127483ENST00000417710B0QZK8
ENSG00000127483ENST00000419490B0QZK5
ENSG00000127483ENST00000419948B0QZK4
ENSG00000127483ENST00000424732Q5SWC8
ENSG00000127483ENST00000437575B0QZK6
ENSG00000127483ENST00000438032X6RGJ2
ENSG00000127483ENST00000443615B0QZK7

Expression (GTEx)

0
50
100
150
200

Protein levels (Protein atlas)

Not detected
Low
Medium
High

References

Pubmed IDYearTitleCitations
203796142010Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score.62
191655272009Prefrontal cortex shotgun proteome analysis reveals altered calcium homeostasis and immune system imbalance in schizophrenia.56
248304162014Profiling of the Chromatin-associated Proteome Identifies HP1BP3 as a Novel Regulator of Cell Cycle Progression.16
265033112016Replication of Epigenetic Postpartum Depression Biomarkers and Variation with Hormone Levels.15
200426022010The middle region of an HP1-binding protein, HP1-BP74, associates with linker DNA at the entry/exit site of nucleosomal DNA.14
251008602014Quantitative profiling of chromatome dynamics reveals a novel role for HP1BP3 in hypoxia-induced oncogenesis.14
208006032010Investigation of genetic susceptibility factors for human longevity - a targeted nonsynonymous SNP study.12
256626032015HP1BP3 is a novel histone H1 related protein with essential roles in viability and growth.10
274254092016HP1BP3, a Chromatin Retention Factor for Co-transcriptional MicroRNA Processing.9
264028432015Proportionate Dwarfism in Mice Lacking Heterochromatin Protein 1 Binding Protein 3 (HP1BP3) Is Associated With Alterations in the Endocrine IGF-1 Pathway.7

Citation

Dessen P

HP1BP3 (heterochromatin protein 1 binding protein 3)

Atlas Genet Cytogenet Oncol Haematol. 2015-08-01

Online version: http://atlasgeneticsoncology.org/gene/55344/hp1bp3