HPF1 (histone PARylation factor 1)

2001-01-01  

Identity

HGNC
LOCATION
4q33
LOCUSID
ALIAS
C4orf27

Other Information

Locus ID:

NCBI: 54969
MIM: 616614
HGNC: 26051
Ensembl: ENSG00000056050

Variants:

dbSNP: 54969
ClinVar: 54969
TCGA: ENSG00000056050
COSMIC: HPF1

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000056050ENST00000393381Q9NWY4

Expression (GTEx)

0
5
10
15
20
25
30
35
40
45
50

Protein levels (Protein atlas)

Not detected
Low
Medium
High

References

Pubmed IDYearTitleCitations
203796142010Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score.62
281907682017Serine ADP-Ribosylation Depends on HPF1.61
270676002016HPF1/C4orf27 Is a PARP-1-Interacting Protein that Regulates PARP-1 ADP-Ribosylation Activity.52
294808022018Serine is the major residue for ADP-ribosylation upon DNA damage.36
320285272020HPF1 completes the PARP active site for DNA damage-induced ADP-ribosylation.0

Citation

Dessen P

HPF1 (histone PARylation factor 1)

Atlas Genet Cytogenet Oncol Haematol. 2001-01-01

Online version: http://atlasgeneticsoncology.org/gene/78372/hpf1