Identity
HGNC
LOCATION
4q34.1
LOCUSID
ALIAS
15-PGDH,PGDH,PGDH1,PHOAR1,SDR36C1
FUSION GENES
Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 3248
MIM: 601688
HGNC: 5154
Ensembl: ENSG00000164120
Variants:
dbSNP: 3248
ClinVar: 3248
TCGA: ENSG00000164120
COSMIC: HPGD
RNA/Proteins
Expression (GTEx)
Pathways
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 37591693 | 2023 | Reclassification of the HPGD p.Ala13Glu variant causing primary hypertrophic osteoarthropathy. | 0 |
| 37591693 | 2023 | Reclassification of the HPGD p.Ala13Glu variant causing primary hypertrophic osteoarthropathy. | 0 |
| 34880125 | 2022 | Epigenetic Silencing of 15-Hydroxyprostaglandin Dehydrogenase by Histone Methyltransferase EHMT2/G9a in Cholangiocarcinoma. | 4 |
| 35813463 | 2022 | Clinical and biochemical characteristics of 12 Chinese primary hypertrophic osteoarthropathy patients with HPGD mutations. | 2 |
| 34880125 | 2022 | Epigenetic Silencing of 15-Hydroxyprostaglandin Dehydrogenase by Histone Methyltransferase EHMT2/G9a in Cholangiocarcinoma. | 4 |
| 35813463 | 2022 | Clinical and biochemical characteristics of 12 Chinese primary hypertrophic osteoarthropathy patients with HPGD mutations. | 2 |
| 33303683 | 2021 | Inhibition of prostaglandin-degrading enzyme 15-PGDH rejuvenates aged muscle mass and strength. | 67 |
| 33303683 | 2021 | Inhibition of prostaglandin-degrading enzyme 15-PGDH rejuvenates aged muscle mass and strength. | 67 |
| 32100450 | 2020 | Association between COX-2 and 15-PGDH polymorphisms and SLE susceptibility. | 7 |
| 32100450 | 2020 | Association between COX-2 and 15-PGDH polymorphisms and SLE susceptibility. | 7 |
| 30931980 | 2019 | miR-21-mediated regulation of 15-hydroxyprostaglandin dehydrogenase in colon cancer. | 10 |
| 31027998 | 2019 | Enzymatic Activity of HPGD in Treg Cells Suppresses Tconv Cells to Maintain Adipose Tissue Homeostasis and Prevent Metabolic Dysfunction. | 39 |
| 31646799 | 2019 | Single nucleotide polymorphism rs2555639 in 15-PGDH and colorectal cancer metastasis. | 1 |
| 30931980 | 2019 | miR-21-mediated regulation of 15-hydroxyprostaglandin dehydrogenase in colon cancer. | 10 |
| 31027998 | 2019 | Enzymatic Activity of HPGD in Treg Cells Suppresses Tconv Cells to Maintain Adipose Tissue Homeostasis and Prevent Metabolic Dysfunction. | 39 |
Citation
Dessen P
HPGD (15-hydroxyprostaglandin dehydrogenase)
Atlas Genet Cytogenet Oncol Haematol. 2007-02-01
Online version: http://atlasgeneticsoncology.org/gene/43840/hpgd
