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HRG (histidine rich glycoprotein)

Identity

Other namesHPRG
HRGP
THPH11
HGNC (Hugo) HRG
LocusID (NCBI) 3273
Atlas_Id 43976
Location 3q27.3  [Link to chromosome band 3q27]
Location_base_pair Starts at 186383741 and ends at 186396029 bp from pter ( according to hg19-Feb_2009)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)HRG   5181
Cards
Entrez_Gene (NCBI)HRG  3273  histidine rich glycoprotein
AliasesHPRG; HRGP; THPH11
GeneCards (Weizmann)HRG
Ensembl hg19 (Hinxton)ENSG00000113905 [Gene_View]  chr3:186383741-186396029 [Contig_View]  HRG [Vega]
Ensembl hg38 (Hinxton)ENSG00000113905 [Gene_View]  chr3:186383741-186396029 [Contig_View]  HRG [Vega]
ICGC DataPortalENSG00000113905
TCGA cBioPortalHRG
AceView (NCBI)HRG
Genatlas (Paris)HRG
WikiGenes3273
SOURCE (Princeton)HRG
Genomic and cartography
GoldenPath hg19 (UCSC)HRG  -     chr3:186383741-186396029 +  3q27.3   [Description]    (hg19-Feb_2009)
GoldenPath hg38 (UCSC)HRG  -     3q27.3   [Description]    (hg38-Dec_2013)
EnsemblHRG - 3q27.3 [CytoView hg19]  HRG - 3q27.3 [CytoView hg38]
Mapping of homologs : NCBIHRG [Mapview hg19]  HRG [Mapview hg38]
OMIM142640   613116   
Gene and transcription
Genbank (Entrez)AI800281 AK313381 BC069574 BC150591 CR749302
RefSeq transcript (Entrez)NM_000412
RefSeq genomic (Entrez)NC_000003 NC_018914 NG_021485 NT_005612 NW_004929311
Consensus coding sequences : CCDS (NCBI)HRG
Cluster EST : UnigeneHs.1498 [ NCBI ]
CGAP (NCI)Hs.1498
Alternative Splicing GalleryENSG00000113905
Gene ExpressionHRG [ NCBI-GEO ]   HRG [ EBI - ARRAY_EXPRESS ]   HRG [ SEEK ]   HRG [ MEM ]
Gene Expression Viewer (FireBrowse)HRG [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)3273
GTEX Portal (Tissue expression)HRG
Protein : pattern, domain, 3D structure
UniProt/SwissProtP04196 (Uniprot)
NextProtP04196  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProP04196
Splice isoforms : SwissVarP04196 (Swissvar)
PhosPhoSitePlusP04196
Domains : Interpro (EBI)Cystatin_dom   
Domain families : Pfam (Sanger)Cystatin (PF00031)   
Domain families : Pfam (NCBI)pfam00031   
Domain families : Smart (EMBL)CY (SM00043)  
DMDM Disease mutations3273
Blocks (Seattle)HRG
SuperfamilyP04196
Human Protein AtlasENSG00000113905
Peptide AtlasP04196
HPRD00812
IPIIPI00022371   
Protein Interaction databases
DIP (DOE-UCLA)P04196
IntAct (EBI)P04196
FunCoupENSG00000113905
BioGRIDHRG
STRING (EMBL)HRG
ZODIACHRG
Ontologies - Pathways
QuickGOP04196
Ontology : AmiGOangiogenesis  platelet degranulation  positive regulation of immune response to tumor cell  serine-type endopeptidase inhibitor activity  cysteine-type endopeptidase inhibitor activity  receptor binding  protein binding  extracellular region  extracellular region  extracellular region  plasma membrane  chemotaxis  negative regulation of cell adhesion  heparin binding  zinc ion binding  negative regulation of cell proliferation  regulation of gene expression  regulation of platelet activation  regulation of platelet activation  negative regulation of lamellipodium assembly  negative regulation of endopeptidase activity  negative regulation of endopeptidase activity  heme transport  negative regulation of angiogenesis  immunoglobulin binding  heme binding  platelet activation  regulation of blood coagulation  negative regulation of cell growth  platelet alpha granule lumen  regulation of actin cytoskeleton organization  negative regulation of cell adhesion mediated by integrin  endolysosome  fibrinolysis  positive regulation of apoptotic process  regulation of protein complex assembly  heparan sulfate proteoglycan binding  negative regulation of blood vessel endothelial cell migration  metal ion binding  regulation of peptidyl-tyrosine phosphorylation  defense response to fungus  positive regulation of focal adhesion assembly  negative regulation of fibrinolysis  extracellular exosome  blood microparticle  negative regulation of vascular endothelial growth factor signaling pathway  positive regulation of blood vessel remodeling  negative regulation of endothelial cell chemotaxis  
Ontology : EGO-EBIangiogenesis  platelet degranulation  positive regulation of immune response to tumor cell  serine-type endopeptidase inhibitor activity  cysteine-type endopeptidase inhibitor activity  receptor binding  protein binding  extracellular region  extracellular region  extracellular region  plasma membrane  chemotaxis  negative regulation of cell adhesion  heparin binding  zinc ion binding  negative regulation of cell proliferation  regulation of gene expression  regulation of platelet activation  regulation of platelet activation  negative regulation of lamellipodium assembly  negative regulation of endopeptidase activity  negative regulation of endopeptidase activity  heme transport  negative regulation of angiogenesis  immunoglobulin binding  heme binding  platelet activation  regulation of blood coagulation  negative regulation of cell growth  platelet alpha granule lumen  regulation of actin cytoskeleton organization  negative regulation of cell adhesion mediated by integrin  endolysosome  fibrinolysis  positive regulation of apoptotic process  regulation of protein complex assembly  heparan sulfate proteoglycan binding  negative regulation of blood vessel endothelial cell migration  metal ion binding  regulation of peptidyl-tyrosine phosphorylation  defense response to fungus  positive regulation of focal adhesion assembly  negative regulation of fibrinolysis  extracellular exosome  blood microparticle  negative regulation of vascular endothelial growth factor signaling pathway  positive regulation of blood vessel remodeling  negative regulation of endothelial cell chemotaxis  
NDEx NetworkHRG
Atlas of Cancer Signalling NetworkHRG
Wikipedia pathwaysHRG
Orthology - Evolution
OrthoDB3273
GeneTree (enSembl)ENSG00000113905
Phylogenetic Trees/Animal Genes : TreeFamHRG
Homologs : HomoloGeneHRG
Homology/Alignments : Family Browser (UCSC)HRG
Gene fusions - Rearrangements
Polymorphisms : SNP, variants
NCBI Variation ViewerHRG [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)HRG
dbVarHRG
ClinVarHRG
1000_GenomesHRG 
Exome Variant ServerHRG
ExAC (Exome Aggregation Consortium)HRG (select the gene name)
Genetic variants : HAPMAP3273
Genomic Variants (DGV)HRG [DGVbeta]
Mutations
ICGC Data PortalHRG 
TCGA Data PortalHRG 
Broad Tumor PortalHRG
OASIS PortalHRG [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICHRG 
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch HRG
DgiDB (Drug Gene Interaction Database)HRG
DoCM (Curated mutations)HRG (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)HRG (select a term)
intoGenHRG
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] 
Diseases
DECIPHER (Syndromes)3:186383741-186396029  ENSG00000113905
CONAN: Copy Number AnalysisHRG 
Mutations and Diseases : HGMDHRG
OMIM142640    613116   
MedgenHRG
Genetic Testing Registry HRG
NextProtP04196 [Medical]
TSGene3273
GENETestsHRG
Huge Navigator HRG [HugePedia]
snp3D : Map Gene to Disease3273
BioCentury BCIQHRG
ClinGenHRG
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD3273
Chemical/Pharm GKB GenePA29455
Clinical trialHRG
Miscellaneous
canSAR (ICR)HRG (select the gene name)
Probes
Litterature
PubMed71 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineHRG
EVEXHRG
GoPubMedHRG
iHOPHRG
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Mon Sep 19 18:53:42 CEST 2016

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