HS3ST2 (heparan sulfate-glucosamine 3-sulfotransferase 2)

2003-02-01  

Identity

HGNC
LOCATION
16p12.2
LOCUSID
ALIAS
30ST2,3OST2

Other Information

Locus ID:

NCBI: 9956
MIM: 604056
HGNC: 5195
Ensembl: ENSG00000122254

Variants:

dbSNP: 9956
ClinVar: 9956
TCGA: ENSG00000122254
COSMIC: HS3ST2

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000122254ENST00000261374Q9Y278
ENSG00000122254ENST00000473392H3BMR2

Expression (GTEx)

0
5
10
15
20

Pathways

PathwaySourceExternal ID
Glycosaminoglycan biosynthesis - heparan sulfate / heparinKEGGko00534
Glycosaminoglycan biosynthesis - heparan sulfate / heparinKEGGhsa00534
MetabolismREACTOMER-HSA-1430728
Metabolism of carbohydratesREACTOMER-HSA-71387
Glycosaminoglycan metabolismREACTOMER-HSA-1630316
Heparan sulfate/heparin (HS-GAG) metabolismREACTOMER-HSA-1638091
HS-GAG biosynthesisREACTOMER-HSA-2022928

Protein levels (Protein atlas)

Not detected
Low
Medium
High

References

Pubmed IDYearTitleCitations
357609822022HS3ST2 expression induces the cell autonomous aggregation of tau.5
357609822022HS3ST2 expression induces the cell autonomous aggregation of tau.5
314072532020CpG Islands Methylation Analysis of CDH11, EphA5, and HS3ST2 Genes in Gastric Adenocarcinoma Patients.11
314072532020CpG Islands Methylation Analysis of CDH11, EphA5, and HS3ST2 Genes in Gastric Adenocarcinoma Patients.11
319039502019Possible role of hsa-miR-194-5p, via regulation of HS3ST2, in the pathogenesis of atopic dermatitis in children.7
319039502019Possible role of hsa-miR-194-5p, via regulation of HS3ST2, in the pathogenesis of atopic dermatitis in children.7
296603722018Heparan sulfate 3-O-sulfotransferase 2 (HS3ST2) displays an unexpected subcellular localization in the plasma membrane.7
302216682018Methylation status of KLF4 and HS3ST2 genes as predictors of endometrial cancer and hyperplastic endometrial lesions.8
296603722018Heparan sulfate 3-O-sulfotransferase 2 (HS3ST2) displays an unexpected subcellular localization in the plasma membrane.7
302216682018Methylation status of KLF4 and HS3ST2 genes as predictors of endometrial cancer and hyperplastic endometrial lesions.8
258423902015HS3ST2 expression is critical for the abnormal phosphorylation of tau in Alzheimer's disease-related tau pathology.52
258423902015HS3ST2 expression is critical for the abnormal phosphorylation of tau in Alzheimer's disease-related tau pathology.52
251985532014Methylation in the promoters of HS3ST2 and CCNA1 genes is associated with cervical cancer in Uygur women in Xinjiang.7
251985532014Methylation in the promoters of HS3ST2 and CCNA1 genes is associated with cervical cancer in Uygur women in Xinjiang.7
242657832013Epigenetic inactivation of heparan sulfate (glucosamine) 3-O-sulfotransferase 2 in lung cancer and its role in tumorigenesis.26

Citation

Dessen P

HS3ST2 (heparan sulfate-glucosamine 3-sulfotransferase 2)

Atlas Genet Cytogenet Oncol Haematol. 2003-02-01

Online version: http://atlasgeneticsoncology.org/gene/40866/hs3st2