HSPA14 (heat shock protein family A (Hsp70) member 14)

2007-04-01  

Identity

HGNC
LOCATION
10p13
LOCUSID
ALIAS
HSP70-4,HSP70L1
FUSION GENES

Other Information

Locus ID:

NCBI: 51182
MIM: 610369
HGNC: 29526
Ensembl: ENSG00000284024

Variants:

dbSNP: 51182
ClinVar: 51182
TCGA: ENSG00000284024
COSMIC: HSPA14

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000284024ENST00000437161B0YIZ1
ENSG00000284024ENST00000493178A0A2R8Y8B9
ENSG00000284024ENST00000640019A0A1W2PQ72

Pathways

PathwaySourceExternal ID
Cellular responses to stressREACTOMER-HSA-2262752
Cellular response to heat stressREACTOMER-HSA-3371556
Regulation of HSF1-mediated heat shock responseREACTOMER-HSA-3371453

References

Pubmed IDYearTitleCitations
163854512006A scan of chromosome 10 identifies a novel locus showing strong association with late-onset Alzheimer disease.69
188187482008Preterm birth in Caucasians is associated with coagulation and inflammation pathway gene variants.31
195275142009Racial disparity in pathophysiologic pathways of preterm birth based on genetic variants.31
145928222004Novel heat shock protein Hsp70L1 activates dendritic cells and acts as a Th1 polarizing adjuvant.29
190193352009Spontaneous preterm birth in African Americans is associated with infection and inflammatory response gene variants.26
217300522011Toll-like receptor 4 (TLR4) is essential for Hsp70-like protein 1 (HSP70L1) to activate dendritic cells and induce Th1 response.26
206898072010Genetic variation and antioxidant response gene expression in the bronchial airway epithelium of smokers at risk for lung cancer.23
212084562011Induction of HSPA4 and HSPA14 by NBS1 overexpression contributes to NBS1-induced in vitro metastatic and transformation activity.8
316167802019Telomerase promotes formation of a telomere protective complex in cancer cells.2

Citation

Dessen P

HSPA14 (heat shock protein family A (Hsp70) member 14)

Atlas Genet Cytogenet Oncol Haematol. 2007-04-01

Online version: http://atlasgeneticsoncology.org/gene/46999/hspa14