Identity
HGNC
LOCATION
10p13
LOCUSID
ALIAS
HSP70-4,HSP70L1
FUSION GENES
Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 51182
MIM: 610369
HGNC: 29526
Ensembl: ENSG00000284024
Variants:
dbSNP: 51182
ClinVar: 51182
TCGA: ENSG00000284024
COSMIC: HSPA14
RNA/Proteins
| Gene ID | Transcript ID | Uniprot |
|---|---|---|
| ENSG00000284024 | ENST00000437161 | B0YIZ1 |
| ENSG00000284024 | ENST00000493178 | A0A2R8Y8B9 |
| ENSG00000284024 | ENST00000640019 | A0A1W2PQ72 |
Pathways
| Pathway | Source | External ID |
|---|---|---|
| Cellular responses to stress | REACTOME | R-HSA-2262752 |
| Cellular response to heat stress | REACTOME | R-HSA-3371556 |
| Regulation of HSF1-mediated heat shock response | REACTOME | R-HSA-3371453 |
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 36845091 | 2023 | Expression of HSPA14 in patients with acute HIV-1 infection and its effect on HIV-1 replication. | 1 |
| 36845091 | 2023 | Expression of HSPA14 in patients with acute HIV-1 infection and its effect on HIV-1 replication. | 1 |
| 30635648 | 2020 | Intracellular HSP70L1 inhibits human dendritic cell maturation by promoting suppressive H3K27me3 and H2AK119Ub1 histone modifications. | 6 |
| 30635648 | 2020 | Intracellular HSP70L1 inhibits human dendritic cell maturation by promoting suppressive H3K27me3 and H2AK119Ub1 histone modifications. | 6 |
| 31616780 | 2019 | Telomerase promotes formation of a telomere protective complex in cancer cells. | 18 |
| 31616780 | 2019 | Telomerase promotes formation of a telomere protective complex in cancer cells. | 18 |
| 21208456 | 2011 | Induction of HSPA4 and HSPA14 by NBS1 overexpression contributes to NBS1-induced in vitro metastatic and transformation activity. | 17 |
| 21730052 | 2011 | Toll-like receptor 4 (TLR4) is essential for Hsp70-like protein 1 (HSP70L1) to activate dendritic cells and induce Th1 response. | 44 |
| 21208456 | 2011 | Induction of HSPA4 and HSPA14 by NBS1 overexpression contributes to NBS1-induced in vitro metastatic and transformation activity. | 17 |
| 21730052 | 2011 | Toll-like receptor 4 (TLR4) is essential for Hsp70-like protein 1 (HSP70L1) to activate dendritic cells and induce Th1 response. | 44 |
| 20689807 | 2010 | Genetic variation and antioxidant response gene expression in the bronchial airway epithelium of smokers at risk for lung cancer. | 27 |
| 20689807 | 2010 | Genetic variation and antioxidant response gene expression in the bronchial airway epithelium of smokers at risk for lung cancer. | 27 |
| 19019335 | 2009 | Spontaneous preterm birth in African Americans is associated with infection and inflammatory response gene variants. | 33 |
| 19527514 | 2009 | Racial disparity in pathophysiologic pathways of preterm birth based on genetic variants. | 34 |
| 19019335 | 2009 | Spontaneous preterm birth in African Americans is associated with infection and inflammatory response gene variants. | 33 |
Citation
Dessen P
HSPA14 (heat shock protein family A (Hsp70) member 14)
Atlas Genet Cytogenet Oncol Haematol. 2007-04-01
Online version: http://atlasgeneticsoncology.org/gene/46999/hspa14
