HSPB7 (heat shock protein family B (small) member 7)

2003-06-01  

Identity

HGNC
HSPB7
LOCATION
1p36.13
LOCUSID
27129
ALIAS
cvHSP
FUSION GENES
Show Gene Fusions

Other Information

Locus ID:

NCBI: 27129
MIM: 610692
HGNC: 5249
Ensembl: ENSG00000173641

Variants:

dbSNP: 27129
ClinVar: 27129
TCGA: ENSG00000173641
COSMIC: HSPB7

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000173641ENST00000311890Q9UBY9
ENSG00000173641ENST00000375718Q8N241
ENSG00000173641ENST00000406363Q68DG0
ENSG00000173641ENST00000411503D3YTC6
ENSG00000173641ENST00000463576C9J5A3
ENSG00000173641ENST00000487046Q9UBY9

Expression (GTEx)

0
500
1000
1500
2000
Adipose - Subcutaneous
Adipose - Visceral
Adrenal Gland
Artery - Aorta
Artery - Tibial
Bladder
Brain - Amygdala
Brain - Anterior cingulate cortex
Brain - Caudate
Brain - Cerebellar Hemisphere
Brain - Cerebellum
Brain - Cortex
Brain - Frontal Cortex
Brain - Hippocampus
Brain - Hypothalamus
Brain - Nucleus accumbens
Brain - Putamen
Brain - Spinal cord
Brain - Substantia nigra
Breast - Mammary Tissue
Cells - Cultured fibroblasts
Cells - EBV - transformed lymphocytes
Cervix - Ectocervix
Cervix - Endocervix
Colon - Sigmoid
Colon - Transverse
Esophagus - Gastroesophageal Junction
Esophagus - Mucosa
Esophagus - Muscularis
Fallopian Tube
Heart - Atrial Appendage
Heart - Left Ventricle
Kidney - Cortex
Kidney - Medulla
Liver
Lung
Minor Salivary Gland
Muscle - Skeletal
Nerve - Tibial
Ovary
Pancreas
Pituitary
Prostate
Skin - Not Sun Exposed
Skin - Sun Exposed
Small Intestine - Terminal Ileum
Spleen
Stomach
Testis
Thyroid
Uterus
Vagina
Whole Blood

Protein levels (Protein atlas)

Not detected
Low
Medium
High
cerebral cortex
cerebellum
hippocampus
caudate
thyroid gland
parathyroid gland
adrenal gland
nasopharynx
bronchus
lung
oral mucosa
salivary gland
esophagus
stomach 1
stomach 2
duodenum
small intestine
colon
rectum
liver
gallbladder
pancreas
kidney
urinary bladder
testis
epididymis
seminal vesicle
prostate
vagina
ovary
fallopian tube
endometrium 1
endometrium 2
cervix, uterine
placenta
breast
heart muscle
smooth muscle
skeletal muscle
soft tissue 1
soft tissue 2
adipose tissue
skin 1
skin 2
appendix
spleen
lymph node
tonsil
bone marrow

References

Pubmed IDYearTitleCitations
199131212009Gene-centric association signals for lipids and apolipoproteins identified via the HumanCVD BeadChip.85
201244412010Common variants in HSPB7 and FRMD4B associated with advanced heart failure.52
209759472010Genetic association study identifies HSPB7 as a risk gene for idiopathic dilated cardiomyopathy.45
209759472010Genetic association study identifies HSPB7 as a risk gene for idiopathic dilated cardiomyopathy.45
217316112011HSPB1, HSPB6, HSPB7 and HSPB8 protect against RhoA GTPase-induced remodeling in tachypaced atrial myocytes.33
194643262009HSPB7 is a SC35 speckle resident small heat shock protein.31
200387962010Cardiac signaling genes exhibit unexpected sequence diversity in sporadic cardiomyopathy, revealing HSPB7 polymorphisms associated with disease.24
208776242010Genetic variants in nuclear-encoded mitochondrial genes influence AIDS progression.17
206280862010Variation at the NFATC2 locus increases the risk of thiazolidinedione-induced edema in the Diabetes REduction Assessment with ramipril and rosiglitazone Medication (DREAM) study.11
258894382015Involvement of BAG3 and HSPB7 loci in various etiologies of systolic heart failure: Results of a European collaboration assembling more than 2000 patients.9

Citation

Dessen P

HSPB7 (heat shock protein family B (small) member 7)

Atlas Genet Cytogenet Oncol Haematol. 2003-06-01

Online version: http://atlasgeneticsoncology.org/gene/40882/hspb7