HSPE1 (heat shock protein family E (Hsp10) member 1)

2003-08-01  

Identity

HGNC
LOCATION
2q33.1
LOCUSID
ALIAS
CPN10,EPF,GROES,HSP10
FUSION GENES

Other Information

Locus ID:

NCBI: 3336
MIM: 600141
HGNC: 5269
Ensembl: ENSG00000115541

Variants:

dbSNP: 3336
ClinVar: 3336
TCGA: ENSG00000115541
COSMIC: HSPE1

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000115541ENST00000233893P61604
ENSG00000115541ENST00000233893A0A384N6A4
ENSG00000115541ENST00000409468B8ZZL8
ENSG00000115541ENST00000409729B8ZZ54

Expression (GTEx)

0
50
100
150
200
250
300
350
400

Protein levels (Protein atlas)

Not detected
Low
Medium
High

References

Pubmed IDYearTitleCitations
118981272002Hereditary spastic paraplegia SPG13 is associated with a mutation in the gene encoding the mitochondrial chaperonin Hsp60.97
124833022003Genomic structure of the human mitochondrial chaperonin genes: HSP60 and HSP10 are localised head to head on chromosome 2 separated by a bidirectional promoter.48
155468852005Heat shock protein 10 inhibits lipopolysaccharide-induced inflammatory mediator production.46
189873172008Chaperonin chamber accelerates protein folding through passive action of preventing aggregation.42
162531462005The expression of HSP60 and HSP10 in large bowel carcinomas with lymph node metastase.38
185002652008Immunohistochemical analysis of possible chemoresistance markers identified by micro-arrays on serous ovarian carcinomas.20
208776242010Genetic variants in nuclear-encoded mitochondrial genes influence AIDS progression.17
172788772006Heat shock protein 10 and signal transduction: a "capsula eburnea" of carcinogenesis?15
213752472011Macromolecular crowding extended to a heptameric system: the Co-chaperonin protein 10.14
286621002017miR-146a, miR-146b, and miR-155 increase expression of IL-6 and IL-8 and support HSP10 in an In vitro sepsis model.13

Citation

Dessen P

HSPE1 (heat shock protein family E (Hsp10) member 1)

Atlas Genet Cytogenet Oncol Haematol. 2003-08-01

Online version: http://atlasgeneticsoncology.org/gene/40889/hspe1