Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 203100
MIM: 610700
HGNC: 26909
Ensembl: ENSG00000169495
Variants:
dbSNP: 203100
ClinVar: 203100
TCGA: ENSG00000169495
COSMIC: HTRA4
RNA/Proteins
| Gene ID | Transcript ID | Uniprot |
|---|---|---|
| ENSG00000169495 | ENST00000302495 | P83105 |
Expression (GTEx)
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 38325051 | 2024 | HtrA4 is required for human trophoblast stem cell differentiation into syncytiotrophoblast. | 0 |
| 38880601 | 2024 | Identification of HTRA4 as a Transcriptional Target of p63 in Trophoblast. | 0 |
| 38325051 | 2024 | HtrA4 is required for human trophoblast stem cell differentiation into syncytiotrophoblast. | 0 |
| 38880601 | 2024 | Identification of HTRA4 as a Transcriptional Target of p63 in Trophoblast. | 0 |
| 37296580 | 2023 | Cellular Functions of High-Temperature Requirement Factor A4 in Placenta. | 1 |
| 37579694 | 2023 | Deficiency of HtrA4 in BeWo cells downregulates angiogenesis through IL-6/JAK/STAT3 signaling. | 0 |
| 37296580 | 2023 | Cellular Functions of High-Temperature Requirement Factor A4 in Placenta. | 1 |
| 37579694 | 2023 | Deficiency of HtrA4 in BeWo cells downregulates angiogenesis through IL-6/JAK/STAT3 signaling. | 0 |
| 34257367 | 2021 | HtrA4 is up-regulated during trophoblast syncytialization and BeWo cells fail to syncytialize without HtrA4. | 9 |
| 34257367 | 2021 | HtrA4 is up-regulated during trophoblast syncytialization and BeWo cells fail to syncytialize without HtrA4. | 9 |
| 32056555 | 2020 | Elevated circulating HtrA4 in preeclampsia may alter endothelial expression of senescence genes. | 10 |
| 32056555 | 2020 | Elevated circulating HtrA4 in preeclampsia may alter endothelial expression of senescence genes. | 10 |
| 30638949 | 2019 | Elevated protease HtrA4 in the maternal circulation of preeclampsia may contribute to endothelial barrier disruption by cleaving key junctional protein VE-cadherin. | 6 |
| 30804477 | 2019 | HtrA4 may play a major role in inhibiting endothelial repair in pregnancy complication preeclampsia. | 9 |
| 31036715 | 2019 | Discerning the mechanism of action of HtrA4: a serine protease implicated in the cell death pathway. | 6 |
Citation
Dessen P
HTRA4 (HtrA serine peptidase 4)
Atlas Genet Cytogenet Oncol Haematol. 0000-00-00
Online version: http://atlasgeneticsoncology.org/gene/52757/htra4
