Identity
HGNC
LOCATION
21q22.3
LOCUSID
ALIAS
B7-H2,B7H2,B7RP-1,B7RP1,B7h,CD275,GL50,ICOS-L,ICOSL,LICOS
FUSION GENES
Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 23308
MIM: 605717
HGNC: 17087
Ensembl: ENSG00000160223
Variants:
dbSNP: 23308
ClinVar: 23308
TCGA: ENSG00000160223
COSMIC: ICOSLG
RNA/Proteins
Expression (GTEx)
Pathways
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 37847858 | 2024 | Epstein-Barr virus-encoded EBNA2 downregulates ICOSL by inducing miR-24 in B-cell lymphoma. | 2 |
| 38081339 | 2024 | ICOSLG acts as an oncogene to promote glycolysis, proliferation, migration, and invasion in gastric cancer cells. | 1 |
| 37847858 | 2024 | Epstein-Barr virus-encoded EBNA2 downregulates ICOSL by inducing miR-24 in B-cell lymphoma. | 2 |
| 38081339 | 2024 | ICOSLG acts as an oncogene to promote glycolysis, proliferation, migration, and invasion in gastric cancer cells. | 1 |
| 37850501 | 2023 | Expression and prognosis of inducible T-cell co-stimulator and its ligand in Chinese stage I-III lung adenocarcinoma patients. | 1 |
| 38077334 | 2023 | Role of the co-stimulatory molecule inducible T-cell co-stimulator ligand (ICOSL) in the progression of experimental metabolic dysfunction-associated steatohepatitis. | 1 |
| 37850501 | 2023 | Expression and prognosis of inducible T-cell co-stimulator and its ligand in Chinese stage I-III lung adenocarcinoma patients. | 1 |
| 38077334 | 2023 | Role of the co-stimulatory molecule inducible T-cell co-stimulator ligand (ICOSL) in the progression of experimental metabolic dysfunction-associated steatohepatitis. | 1 |
| 33662168 | 2021 | Mesenchymal stem cells regulate type 2 innate lymphoid cells via regulatory T cells through ICOS-ICOSL interaction. | 10 |
| 34185422 | 2021 | Activated neutrophils polarize protumorigenic interleukin-17A-producing T helper subsets through TNF-α-B7-H2-dependent pathway in human gastric cancer. | 9 |
| 33662168 | 2021 | Mesenchymal stem cells regulate type 2 innate lymphoid cells via regulatory T cells through ICOS-ICOSL interaction. | 10 |
| 34185422 | 2021 | Activated neutrophils polarize protumorigenic interleukin-17A-producing T helper subsets through TNF-α-B7-H2-dependent pathway in human gastric cancer. | 9 |
| 31998801 | 2020 | The ICOSL Expression Predicts Better Prognosis for Nasopharyngeal Carcinoma via Enhancing Oncoimmunity. | 1 |
| 33033255 | 2020 | Structural characterization of the ICOS/ICOS-L immune complex reveals high molecular mimicry by therapeutic antibodies. | 17 |
| 33051240 | 2020 | Dysregulated NF-κB-Dependent ICOSL Expression in Human Dendritic Cell Vaccines Impairs T-cell Responses in Patients with Melanoma. | 12 |
Citation
Dessen P
ICOSLG (inducible T cell costimulator ligand)
Atlas Genet Cytogenet Oncol Haematol. 2007-02-01
Online version: http://atlasgeneticsoncology.org/gene/46042/icoslg
