IDI1 (isopentenyl-diphosphate delta isomerase 1)

2014-11-01  

Identity

HGNC
LOCATION
10p15.3
LOCUSID
ALIAS
IPP1,IPPI1
FUSION GENES

Other Information

Locus ID:

NCBI: 3422
MIM: 604055
HGNC: 5387
Ensembl: ENSG00000067064

Variants:

dbSNP: 3422
ClinVar: 3422
TCGA: ENSG00000067064
COSMIC: IDI1

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000067064ENST00000381344Q13907
ENSG00000067064ENST00000427898C9JD53
ENSG00000067064ENST00000429642Q13907

Expression (GTEx)

0
50
100
150

Pathways

PathwaySourceExternal ID
Terpenoid backbone biosynthesisKEGGko00900
Terpenoid backbone biosynthesisKEGGhsa00900
Metabolic pathwaysKEGGhsa01100
C5 isoprenoid biosynthesis, mevalonate pathwayKEGGhsa_M00095
C5 isoprenoid biosynthesis, mevalonate pathwayKEGGM00095
MetabolismREACTOMER-HSA-1430728
Metabolism of lipids and lipoproteinsREACTOMER-HSA-556833
Cholesterol biosynthesisREACTOMER-HSA-191273
Regulation of cholesterol biosynthesis by SREBP (SREBF)REACTOMER-HSA-1655829
Activation of gene expression by SREBF (SREBP)REACTOMER-HSA-2426168

Protein levels (Protein atlas)

Not detected
Low
Medium
High

References

Pubmed IDYearTitleCitations
186604892008Multiple genetic variants along candidate pathways influence plasma high-density lipoprotein cholesterol concentrations.26
208776242010Genetic variants in nuclear-encoded mitochondrial genes influence AIDS progression.17
209556882010Segmental copy-number gain within the region of isopentenyl diphosphate isomerase genes in sporadic amyotrophic lateral sclerosis.7
259507362015Isopentenyl diphosphate isomerase, a cholesterol synthesizing enzyme, is localized in Lewy bodies.3
146290382003Isopentenyl-diphosphate isomerases in human and mouse: evolutionary analysis of a mammalian gene duplication.2
305672952018<i>Idi1</i> and <i>Hmgcs2</i> Are Affected by Stretch in HL-1 Atrial Myocytes.1

Citation

Dessen P

IDI1 (isopentenyl-diphosphate delta isomerase 1)

Atlas Genet Cytogenet Oncol Haematol. 2014-11-01

Online version: http://atlasgeneticsoncology.org/gene/64497/idi1