Identity
HGNC
LOCATION
2q24.2
LOCUSID
ALIAS
AGS7,Hlcd,IDDM19,MDA-5,MDA5,RLR-2,SGMRT1
FUSION GENES
Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 64135
MIM: 606951
HGNC: 18873
Ensembl: ENSG00000115267
Variants:
dbSNP: 64135
ClinVar: 64135
TCGA: ENSG00000115267
COSMIC: IFIH1
RNA/Proteins
| Gene ID | Transcript ID | Uniprot |
|---|---|---|
| ENSG00000115267 | ENST00000421365 | Q9BYX4 |
| ENSG00000115267 | ENST00000648433 | A0A3B3IRK8 |
| ENSG00000115267 | ENST00000649979 | Q9BYX4 |
Expression (GTEx)
Pathways
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 37197957 | 2024 | Anti-melanoma Differentiation-associated Gene 5 Antibody-positive Dermatomyositis Presenting as Refractory Gingivitis at the First Clinical Manifestation. | 0 |
| 37740789 | 2024 | MDA5 Enhances Invasive Candida albicans Infection by Regulating Macrophage Apoptosis and Phagocytosis/Killing Functions. | 1 |
| 37863517 | 2024 | Hepatitis C virus NS5B triggers an MDA5-mediated innate immune response by producing dsRNA without the replication of viral genomes. | 1 |
| 38182800 | 2024 | Global trends in research of melanoma differentiation-associated gene 5: a bibliometric analysis from 2002 to 2022. | 0 |
| 38309507 | 2024 | Contrasting functions of ATP hydrolysis by MDA5 and LGP2 in viral RNA sensing. | 2 |
| 38399950 | 2024 | Histone H1.2 Inhibited EMCV Replication through Enhancing MDA5-Mediated IFN-β Signaling Pathway. | 0 |
| 38579189 | 2024 | Genome-Wide Association Study Identifies IFIH1 and HLA-DQB1*05:02 Loci Associated With Anti-NMDAR Encephalitis. | 1 |
| 38663254 | 2024 | Mammalian reovirus µ1 protein attenuates RIG-I and MDA5-mediated signaling transduction by blocking IRF3 phosphorylation and nuclear translocation. | 0 |
| 37197957 | 2024 | Anti-melanoma Differentiation-associated Gene 5 Antibody-positive Dermatomyositis Presenting as Refractory Gingivitis at the First Clinical Manifestation. | 0 |
| 37740789 | 2024 | MDA5 Enhances Invasive Candida albicans Infection by Regulating Macrophage Apoptosis and Phagocytosis/Killing Functions. | 1 |
| 37863517 | 2024 | Hepatitis C virus NS5B triggers an MDA5-mediated innate immune response by producing dsRNA without the replication of viral genomes. | 1 |
| 38182800 | 2024 | Global trends in research of melanoma differentiation-associated gene 5: a bibliometric analysis from 2002 to 2022. | 0 |
| 38309507 | 2024 | Contrasting functions of ATP hydrolysis by MDA5 and LGP2 in viral RNA sensing. | 2 |
| 38399950 | 2024 | Histone H1.2 Inhibited EMCV Replication through Enhancing MDA5-Mediated IFN-β Signaling Pathway. | 0 |
| 38579189 | 2024 | Genome-Wide Association Study Identifies IFIH1 and HLA-DQB1*05:02 Loci Associated With Anti-NMDAR Encephalitis. | 1 |
Citation
Dessen P
IFIH1 (interferon induced with helicase C domain 1)
Atlas Genet Cytogenet Oncol Haematol. 2003-02-01
Online version: http://atlasgeneticsoncology.org/gene/41325/ifih1
