IFIT2 (interferon induced protein with tetratricopeptide repeats 2)

2007-07-01  

Identity

HGNC
LOCATION
10q23.31
LOCUSID
ALIAS
G10P2,GARG-39,IFI-54,IFI-54K,IFI54,IFIT-2,ISG-54,ISG-54

Other Information

Locus ID:

NCBI: 3433
MIM: 147040
HGNC: 5409
Ensembl: ENSG00000119922

Variants:

dbSNP: 3433
ClinVar: 3433
TCGA: ENSG00000119922
COSMIC: IFIT2

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000119922ENST00000371826P09913
ENSG00000119922ENST00000611722A0A087X279
ENSG00000119922ENST00000638108P09913

Expression (GTEx)

0
5
10
15
20
25
30
35
40

Pathways

PathwaySourceExternal ID
Immune SystemREACTOMER-HSA-168256
Cytokine Signaling in Immune systemREACTOMER-HSA-1280215
Interferon SignalingREACTOMER-HSA-913531
Interferon alpha/beta signalingREACTOMER-HSA-909733

Protein levels (Protein atlas)

Not detected
Low
Medium
High

References

Pubmed IDYearTitleCitations
370638542023MiR-199a-5P promotes osteogenic differentiation of human stem cells from apical papilla via targeting IFIT2 in apical periodontitis.3
370638542023MiR-199a-5P promotes osteogenic differentiation of human stem cells from apical papilla via targeting IFIT2 in apical periodontitis.3
339423662021Super-enhancer-associated long noncoding RNA RP11-569A11.1 inhibited cell progression and metastasis by regulating IFIT2 in colorectal cancer.7
342152582021PML-II regulates ERK and AKT signal activation and IFNα-induced cell death.5
347632332021Comprehensive analysis of the prognosis and biological significance for IFIT family in skin cutaneous melanoma.7
348849212021Identified Three Interferon Induced Proteins as Novel Biomarkers of Human Ischemic Cardiomyopathy.6
339423662021Super-enhancer-associated long noncoding RNA RP11-569A11.1 inhibited cell progression and metastasis by regulating IFIT2 in colorectal cancer.7
342152582021PML-II regulates ERK and AKT signal activation and IFNα-induced cell death.5
347632332021Comprehensive analysis of the prognosis and biological significance for IFIT family in skin cutaneous melanoma.7
348849212021Identified Three Interferon Induced Proteins as Novel Biomarkers of Human Ischemic Cardiomyopathy.6
321249542020Overexpression of IFIT2 inhibits the proliferation of chronic myeloid leukemia cells by regulating the BCR‑ABL/AKT/mTOR pathway.5
328395372020Influenza virus repurposes the antiviral protein IFIT2 to promote translation of viral mRNAs.45
321249542020Overexpression of IFIT2 inhibits the proliferation of chronic myeloid leukemia cells by regulating the BCR‑ABL/AKT/mTOR pathway.5
328395372020Influenza virus repurposes the antiviral protein IFIT2 to promote translation of viral mRNAs.45
308757922019Baicalein Suppresses Stem Cell-Like Characteristics in Radio- and Chemoresistant MDA-MB-231 Human Breast Cancer Cells through Up-Regulation of IFIT2.37

Citation

Dessen P

IFIT2 (interferon induced protein with tetratricopeptide repeats 2)

Atlas Genet Cytogenet Oncol Haematol. 2007-07-01

Online version: http://atlasgeneticsoncology.org/gene/47644/ifit2