Identity
HGNC
LOCATION
9p21.3
LOCUSID
ALIAS
IFL,IFN,IFN-ALPHA,IFN-alphaD,IFNA13,IFNA@,leIF
Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 3439
MIM: 147660
HGNC: 5417
Ensembl: ENSG00000197919
Variants:
dbSNP: 3439
ClinVar: 3439
TCGA: ENSG00000197919
COSMIC: IFNA1
RNA/Proteins
| Gene ID | Transcript ID | Uniprot |
|---|---|---|
| ENSG00000197919 | ENST00000276927 | P01562 |
| ENSG00000197919 | ENST00000276927 | L0N195 |
Expression (GTEx)
Pathways
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 38051494 | 2024 | Role of IFN-α in Rheumatoid Arthritis. | 2 |
| 38127913 | 2024 | Hemolysis-driven IFNα production impairs erythropoiesis by negatively regulating EPO signaling in sickle cell disease. | 2 |
| 38387232 | 2024 | Interferon-α induces differentiation of cancer stem cells and immunosuppression in hepatocellular carcinoma by upregulating CXCL8 secretion. | 3 |
| 38424312 | 2024 | Severe COVID-19 and long COVID are associated with high expression of STING, cGAS and IFN-α. | 1 |
| 38605949 | 2024 | Enhanced GATA4 expression in senescent systemic lupus erythematosus monocytes promotes high levels of IFNα production. | 0 |
| 38675842 | 2024 | The Expression Levels of TREX1 and IFN-α Are Associated with Immune Reconstitution in HIV-1-Infected Individuals. | 0 |
| 38051494 | 2024 | Role of IFN-α in Rheumatoid Arthritis. | 2 |
| 38127913 | 2024 | Hemolysis-driven IFNα production impairs erythropoiesis by negatively regulating EPO signaling in sickle cell disease. | 2 |
| 38387232 | 2024 | Interferon-α induces differentiation of cancer stem cells and immunosuppression in hepatocellular carcinoma by upregulating CXCL8 secretion. | 3 |
| 38424312 | 2024 | Severe COVID-19 and long COVID are associated with high expression of STING, cGAS and IFN-α. | 1 |
| 38605949 | 2024 | Enhanced GATA4 expression in senescent systemic lupus erythematosus monocytes promotes high levels of IFNα production. | 0 |
| 38675842 | 2024 | The Expression Levels of TREX1 and IFN-α Are Associated with Immune Reconstitution in HIV-1-Infected Individuals. | 0 |
| 36335528 | 2023 | Chinese Pedigree of Chronic Mucocutaneous Candidiasis Due to STAT1 Gain-of-Function Mutation: A Case Study and Literature Review. | 1 |
| 36681180 | 2023 | Mechanism of SUMOylation-Mediated Regulation of Type I IFN Expression. | 2 |
| 38077311 | 2023 | Endosomal trafficking inhibitor EGA can control TLR7-mediated IFNα expression by human plasmacytoid dendritic cells. | 0 |
Citation
Dessen P
IFNA1 (interferon alpha 1)
Atlas Genet Cytogenet Oncol Haematol. 2003-08-01
Online version: http://atlasgeneticsoncology.org/gene/40920/ifna1
