IFT27 (intraflagellar transport 27)

2003-12-01  

Identity

HGNC
LOCATION
22q12.3
LOCUSID
ALIAS
BBS19,FAP156,RABL4,RAYL
FUSION GENES

Other Information

Locus ID:

NCBI: 11020
MIM: 615870
HGNC: 18626
Ensembl: ENSG00000100360

Variants:

dbSNP: 11020
ClinVar: 11020
TCGA: ENSG00000100360
COSMIC: IFT27

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000100360ENST00000340630Q9BW83
ENSG00000100360ENST00000415653H0Y6C7
ENSG00000100360ENST00000417951F5GZ09
ENSG00000100360ENST00000430701B1AH58
ENSG00000100360ENST00000433985Q9BW83
ENSG00000100360ENST00000440696B1AH56

Expression (GTEx)

0
5
10
15
20
25
30
35
40
45
50

Pathways

PathwaySourceExternal ID
Organelle biogenesis and maintenanceREACTOMER-HSA-1852241
Cilium AssemblyREACTOMER-HSA-5617833
Intraflagellar transportREACTOMER-HSA-5620924

Protein levels (Protein atlas)

Not detected
Low
Medium
High

References

Pubmed IDYearTitleCitations
348886422022Impaired cooperation between IFT74/BBS22-IFT81 and IFT25-IFT27/BBS19 causes Bardet-Biedl syndrome.14
348886422022Impaired cooperation between IFT74/BBS22-IFT81 and IFT25-IFT27/BBS19 causes Bardet-Biedl syndrome.14
297043042018Loss of function IFT27 variants associated with an unclassified lethal fetal ciliopathy with renal agenesis.10
297043042018Loss of function IFT27 variants associated with an unclassified lethal fetal ciliopathy with renal agenesis.10
244887702014IFT27, encoding a small GTPase component of IFT particles, is mutated in a consanguineous family with Bardet-Biedl syndrome.72
244887702014IFT27, encoding a small GTPase component of IFT particles, is mutated in a consanguineous family with Bardet-Biedl syndrome.72

Citation

Dessen P

IFT27 (intraflagellar transport 27)

Atlas Genet Cytogenet Oncol Haematol. 2003-12-01

Online version: http://atlasgeneticsoncology.org/gene/42018/ift27