Identity
HGNC
LOCATION
Xq13.1
LOCUSID
ALIAS
ALPHA-4,IBP1,alpha4
FUSION GENES
Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 3476
MIM: 300139
HGNC: 5461
Ensembl: ENSG00000089289
Variants:
dbSNP: 3476
ClinVar: 3476
TCGA: ENSG00000089289
COSMIC: IGBP1
RNA/Proteins
| Gene ID | Transcript ID | Uniprot |
|---|---|---|
| ENSG00000089289 | ENST00000342206 | P78318 |
| ENSG00000089289 | ENST00000356413 | P78318 |
Expression (GTEx)
Pathways
| Pathway | Source | External ID |
|---|---|---|
| Autophagy - animal | KEGG | ko04140 |
| Autophagy - animal | KEGG | hsa04140 |
| Autophagy - other | KEGG | ko04136 |
| Autophagy - other | KEGG | hsa04136 |
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 31809976 | 2020 | Molecular profiling of thymoma with myasthenia gravis: Risk factors of developing myasthenia gravis in thymoma patients. | 10 |
| 32183589 | 2020 | Plasma immunoglobulin binding protein 1 as a predictor of development of lupus nephritis. | 2 |
| 31809976 | 2020 | Molecular profiling of thymoma with myasthenia gravis: Risk factors of developing myasthenia gravis in thymoma patients. | 10 |
| 32183589 | 2020 | Plasma immunoglobulin binding protein 1 as a predictor of development of lupus nephritis. | 2 |
| 31137925 | 2019 | Immunoglobulin Binding Protein 1 as a Potential Urine Biomarker in Patients with Lupus Nephritis. | 6 |
| 31137925 | 2019 | Immunoglobulin Binding Protein 1 as a Potential Urine Biomarker in Patients with Lupus Nephritis. | 6 |
| 26876307 | 2016 | Epithelial membrane protein 2 regulates sphingosylphosphorylcholine-induced keratin 8 phosphorylation and reorganization: Changes of PP2A expression by interaction with alpha4 and caveolin-1 in lung cancer cells. | 9 |
| 27169767 | 2016 | The three Type 2A protein phosphatases, PP2Ac, PP4c and PP6c, are differentially regulated by Alpha4. | 8 |
| 26876307 | 2016 | Epithelial membrane protein 2 regulates sphingosylphosphorylcholine-induced keratin 8 phosphorylation and reorganization: Changes of PP2A expression by interaction with alpha4 and caveolin-1 in lung cancer cells. | 9 |
| 27169767 | 2016 | The three Type 2A protein phosphatases, PP2Ac, PP4c and PP6c, are differentially regulated by Alpha4. | 8 |
| 25876659 | 2015 | Dominant negative form of alpha4 inhibits the BCR crosslinking-induced phosphorylation of Bcl-xL and apoptosis in an immature B cell line WEHI-231. | 2 |
| 25876659 | 2015 | Dominant negative form of alpha4 inhibits the BCR crosslinking-induced phosphorylation of Bcl-xL and apoptosis in an immature B cell line WEHI-231. | 2 |
| 24145130 | 2014 | Progestin-inducible EDD E3 ubiquitin ligase binds to α4 phosphoprotein to regulate ubiquitination and degradation of protein phosphatase PP2Ac. | 10 |
| 24388773 | 2014 | α4 contributes to bladder urothelial carcinoma cell invasion and/or metastasis via regulation of E-cadherin and is a predictor of outcome in bladder urothelial carcinoma patients. | 7 |
| 25207814 | 2014 | MID1 catalyzes the ubiquitination of protein phosphatase 2A and mutations within its Bbox1 domain disrupt polyubiquitination of alpha4 but not of PP2Ac. | 8 |
Citation
Dessen P
IGBP1 (immunoglobulin binding protein 1)
Atlas Genet Cytogenet Oncol Haematol. 2010-06-01
Online version: http://atlasgeneticsoncology.org/gene/51526/igbp1
