Identity
HGNC
LOCATION
4q12
LOCUSID
ALIAS
AGM,FSTL2,IBP-7,IGFBP-7,IGFBP-7v,IGFBPRP1,MAC25,PSF,RAMSVPS,TAF
FUSION GENES
Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 3490
MIM: 602867
HGNC: 5476
Ensembl: ENSG00000163453
Variants:
dbSNP: 3490
ClinVar: 3490
TCGA: ENSG00000163453
COSMIC: IGFBP7
RNA/Proteins
| Gene ID | Transcript ID | Uniprot |
|---|---|---|
| ENSG00000163453 | ENST00000295666 | Q16270 |
| ENSG00000163453 | ENST00000514062 | Q16270 |
Expression (GTEx)
Pathways
| Pathway | Source | External ID |
|---|---|---|
| Cellular responses to stress | REACTOME | R-HSA-2262752 |
| Cellular Senescence | REACTOME | R-HSA-2559583 |
| Senescence-Associated Secretory Phenotype (SASP) | REACTOME | R-HSA-2559582 |
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 38218180 | 2024 | Structural insight into CD93 recognition by IGFBP7. | 1 |
| 38840498 | 2024 | IGFBP7 promotes endothelial cell repair in the recovery phase of acute lung injury. | 0 |
| 38218180 | 2024 | Structural insight into CD93 recognition by IGFBP7. | 1 |
| 38840498 | 2024 | IGFBP7 promotes endothelial cell repair in the recovery phase of acute lung injury. | 0 |
| 37270777 | 2023 | METTL3-mediated m(6)A modification of IGFBP7-OT promotes osteoarthritis progression by regulating the DNMT1/DNMT3a-IGFBP7 axis. | 3 |
| 37298628 | 2023 | IGFBP7 Fuels the Glycolytic Metabolism in B-Cell Precursor Acute Lymphoblastic Leukemia by Sustaining Activation of the IGF1R-Akt-GLUT1 Axis. | 2 |
| 37304887 | 2023 | The diagnostic value of serum insulin-like growth factor binding protein 7 in gastric cancer. | 3 |
| 37316358 | 2023 | IGFBP-7 secreted by adipose-derived stem cells inhibits keloid formation via the BRAF/MEK/ERK signaling pathway. | 4 |
| 37714372 | 2023 | Depletion of Igfbp7 alleviates zebrafish NAFLD progression through inhibiting hepatic ferroptosis. | 2 |
| 37270777 | 2023 | METTL3-mediated m(6)A modification of IGFBP7-OT promotes osteoarthritis progression by regulating the DNMT1/DNMT3a-IGFBP7 axis. | 3 |
| 37298628 | 2023 | IGFBP7 Fuels the Glycolytic Metabolism in B-Cell Precursor Acute Lymphoblastic Leukemia by Sustaining Activation of the IGF1R-Akt-GLUT1 Axis. | 2 |
| 37304887 | 2023 | The diagnostic value of serum insulin-like growth factor binding protein 7 in gastric cancer. | 3 |
| 37316358 | 2023 | IGFBP-7 secreted by adipose-derived stem cells inhibits keloid formation via the BRAF/MEK/ERK signaling pathway. | 4 |
| 37714372 | 2023 | Depletion of Igfbp7 alleviates zebrafish NAFLD progression through inhibiting hepatic ferroptosis. | 2 |
| 35076852 | 2022 | Association of insulin-like growth factor binding protein-7 promoter methylation with esophageal cancer in peripheral blood. | 2 |
Citation
Dessen P
IGFBP7 (insulin like growth factor binding protein 7)
Atlas Genet Cytogenet Oncol Haematol. 2003-02-01
Online version: http://atlasgeneticsoncology.org/gene/40934/igfbp7
