IL17D (interleukin 17D)

2012-03-01  

Identity

HGNC
IL17D
LOCATION
13q12.11
LOCUSID
53342
ALIAS
IL-17D
FUSION GENES
Show Gene Fusions

Other Information

Locus ID:

NCBI: 53342
MIM: 607587
HGNC: 5984
Ensembl: ENSG00000172458

Variants:

dbSNP: 53342
ClinVar: 53342
TCGA: ENSG00000172458
COSMIC: IL17D

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000172458ENST00000304920Q8TAD2
ENSG00000172458ENST00000468605A0A087WWZ4
ENSG00000172458ENST00000498088A0A087WW17

Expression (GTEx)

0
10
20
30
40
50
60
70
80
Adipose - Subcutaneous
Adipose - Visceral
Adrenal Gland
Artery - Aorta
Artery - Tibial
Bladder
Brain - Amygdala
Brain - Anterior cingulate cortex
Brain - Caudate
Brain - Cerebellar Hemisphere
Brain - Cerebellum
Brain - Cortex
Brain - Frontal Cortex
Brain - Hippocampus
Brain - Hypothalamus
Brain - Nucleus accumbens
Brain - Putamen
Brain - Spinal cord
Brain - Substantia nigra
Breast - Mammary Tissue
Cells - Cultured fibroblasts
Cells - EBV - transformed lymphocytes
Cervix - Ectocervix
Cervix - Endocervix
Colon - Sigmoid
Colon - Transverse
Esophagus - Gastroesophageal Junction
Esophagus - Mucosa
Esophagus - Muscularis
Fallopian Tube
Heart - Atrial Appendage
Heart - Left Ventricle
Kidney - Cortex
Kidney - Medulla
Liver
Lung
Minor Salivary Gland
Muscle - Skeletal
Nerve - Tibial
Ovary
Pancreas
Pituitary
Prostate
Skin - Not Sun Exposed
Skin - Sun Exposed
Small Intestine - Terminal Ileum
Spleen
Stomach
Testis
Thyroid
Uterus
Vagina
Whole Blood

Pathways

PathwaySourceExternal ID
Cytokine-cytokine receptor interactionKEGGko04060
Jak-STAT signaling pathwayKEGGko04630
Cytokine-cytokine receptor interactionKEGGhsa04060
Jak-STAT signaling pathwayKEGGhsa04630
Th17 cell differentiationKEGGko04659
Th17 cell differentiationKEGGhsa04659
IL-17 signaling pathwayKEGGko04657
IL-17 signaling pathwayKEGGhsa04657

References

Pubmed IDYearTitleCitations
120973642002Cutting edge: IL-17D, a novel member of the IL-17 family, stimulates cytokine production and inhibits hemopoiesis.61
221563482012IL-27 enhances LPS-induced proinflammatory cytokine production via upregulation of TLR4 expression and signaling in human monocytes.33
202374962010New genetic associations detected in a host response study to hepatitis B vaccine.27
247944412014Interleukin-17D mediates tumor rejection through recruitment of natural killer cells.27
275458892016Nrf2 Induces IL-17D to Mediate Tumor and Virus Surveillance.22
234904202013The effects of IL-17 upon human natural killer cells.8
286855462017Expression of inflammatory cytokines in ovarian epithelial cancer and their correlation.2

Citation

Dessen P

IL17D (interleukin 17D)

Atlas Genet Cytogenet Oncol Haematol. 2012-03-01

Online version: http://atlasgeneticsoncology.org/gene/52608/il17d