Identity
HGNC
LOCATION
2q12.1
LOCUSID
ALIAS
CD218a,CDw218a,IL-18R-alpha,IL-18Ralpha,IL-1Rrp,IL18RA,IL18Ralpha2,IL1RRP
FUSION GENES
Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 8809
MIM: 604494
HGNC: 5988
Ensembl: ENSG00000115604
Variants:
dbSNP: 8809
ClinVar: 8809
TCGA: ENSG00000115604
COSMIC: IL18R1
RNA/Proteins
| Gene ID | Transcript ID | Uniprot |
|---|---|---|
| ENSG00000115604 | ENST00000233957 | Q13478 |
| ENSG00000115604 | ENST00000334376 | Q86YL8 |
| ENSG00000115604 | ENST00000409599 | Q13478 |
| ENSG00000115604 | ENST00000410040 | Q13478 |
Expression (GTEx)
Pathways
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 33103874 | 2023 | Increased expression of serum IL-18 and IL-18R in newly diagnosed type 2 diabetes mellitus. | 2 |
| 33103874 | 2023 | Increased expression of serum IL-18 and IL-18R in newly diagnosed type 2 diabetes mellitus. | 2 |
| 33522333 | 2022 | IL18-family Genes Polymorphism Is Associated with the Risk of Myocardial Infarction and IL18 Concentration in Patients with Coronary Artery Disease. | 2 |
| 36544782 | 2022 | Downregulation of T-cell cytotoxic marker IL18R1 promotes cancer proliferation and migration and is associated with dismal prognosis and immunity in lung squamous cell carcinoma. | 11 |
| 33522333 | 2022 | IL18-family Genes Polymorphism Is Associated with the Risk of Myocardial Infarction and IL18 Concentration in Patients with Coronary Artery Disease. | 2 |
| 36544782 | 2022 | Downregulation of T-cell cytotoxic marker IL18R1 promotes cancer proliferation and migration and is associated with dismal prognosis and immunity in lung squamous cell carcinoma. | 11 |
| 32193584 | 2020 | IL-18/IL-18R1 promotes circulating fibrocyte differentiation in the aging population. | 4 |
| 32193584 | 2020 | IL-18/IL-18R1 promotes circulating fibrocyte differentiation in the aging population. | 4 |
| 30990817 | 2019 | Associations of variants In the hexokinase 1 and interleukin 18 receptor regions with oxyhemoglobin saturation during sleep. | 18 |
| 30990817 | 2019 | Associations of variants In the hexokinase 1 and interleukin 18 receptor regions with oxyhemoglobin saturation during sleep. | 18 |
| 28922563 | 2018 | Role of IL-18 in atopic asthma is determined by balance of IL-18/IL-18BP/IL-18R. | 8 |
| 28922563 | 2018 | Role of IL-18 in atopic asthma is determined by balance of IL-18/IL-18BP/IL-18R. | 8 |
| 28395725 | 2017 | [Elevated IL-18, IL-18 binding protein and IL-18 receptor in eosinophil-enriched blood cells in patients with asthma]. | 0 |
| 28395725 | 2017 | [Elevated IL-18, IL-18 binding protein and IL-18 receptor in eosinophil-enriched blood cells in patients with asthma]. | 0 |
| 26566691 | 2016 | Polymorphisms of ST2-IL18R1-IL18RAP gene cluster: a new risk for autoimmune thyroid diseases. | 3 |
Citation
Dessen P
IL18R1 (interleukin 18 receptor 1)
Atlas Genet Cytogenet Oncol Haematol. 2003-11-01
Online version: http://atlasgeneticsoncology.org/gene/40948/il18r1
