IL1F10 (interleukin 1 family member 10)

2018-02-01  

Identity

HGNC
LOCATION
2q14.1
LOCUSID
ALIAS
FIL1-theta,FKSG75,IL-1HY2,IL-38,IL1-theta,IL1HY2

Other Information

Locus ID:

NCBI: 84639
MIM: 615296
HGNC: 15552
Ensembl: ENSG00000136697

Variants:

dbSNP: 84639
ClinVar: 84639
TCGA: ENSG00000136697
COSMIC: IL1F10

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000136697ENST00000341010Q8WWZ1
ENSG00000136697ENST00000393197Q8WWZ1

Expression (GTEx)

0
5
10
15

Pathways

PathwaySourceExternal ID
Immune SystemREACTOMER-HSA-168256
Cytokine Signaling in Immune systemREACTOMER-HSA-1280215
Signaling by InterleukinsREACTOMER-HSA-449147

References

Pubmed IDYearTitleCitations
199131212009Gene-centric association signals for lipids and apolipoproteins identified via the HumanCVD BeadChip.85
223154222012IL-38 binds to the IL-36 receptor and has biological effects on immune cells similar to IL-36 receptor antagonist.68
179751192008Association of gene variants with incident myocardial infarction in the Cardiovascular Health Study.65
202374962010New genetic associations detected in a host response study to hepatitis B vaccine.27
163612752006Replication of association of IL1 gene complex members with ankylosing spondylitis in Taiwanese Chinese.23
180636732008Prospective meta-analysis of interleukin 1 gene complex polymorphisms confirms associations with ankylosing spondylitis.21
263143752015Brief Report: Interleukin-38 Exerts Antiinflammatory Functions and Is Associated With Disease Activity in Systemic Lupus Erythematosus.21
282889642017IL-38 overexpression induces anti-inflammatory effects in mice arthritis models and in human macrophages in vitro.18
190230992009Gene variants associated with ischemic stroke: the cardiovascular health study.16
209755732011Interleukin 1 β (IL-1B) and IL-1 antagonist receptor (IL-1RN) gene polymorphisms are associated with the genetic susceptibility and steroid dependence in patients with ulcerative colitis.13

Citation

Dessen P

IL1F10 (interleukin 1 family member 10)

Atlas Genet Cytogenet Oncol Haematol. 2018-02-01

Online version: http://atlasgeneticsoncology.org/gene/57263/il1f10