IL26 (interleukin 26)

2014-01-01  

Identity

HGNC
LOCATION
12q15
LOCUSID
ALIAS
AK155,IL-26
FUSION GENES

Other Information

Locus ID:

NCBI: 55801
MIM: 605679
HGNC: 17119
Ensembl: ENSG00000111536

Variants:

dbSNP: 55801
ClinVar: 55801
TCGA: ENSG00000111536
COSMIC: IL26

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000111536ENST00000229134Q9NPH9

Expression (GTEx)

0
1

Pathways

PathwaySourceExternal ID
Cytokine-cytokine receptor interactionKEGGko04060
Cytokine-cytokine receptor interactionKEGGhsa04060

References

Pubmed IDYearTitleCitations
177034122007Genetic susceptibility to respiratory syncytial virus bronchiolitis is predominantly associated with innate immune genes.100
201767342010Comparative genetic analysis of inflammatory bowel disease and type 1 diabetes implicates multiple loci with opposite effects.66
203796142010Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score.62
230558312012IL-26 is overexpressed in rheumatoid arthritis and induces proinflammatory cytokine production and Th17 cell generation.47
147646632004Cutting edge: IL-26 signals through a novel receptor complex composed of IL-20 receptor 1 and IL-10 receptor 2.46
151786812004The T-cell lymphokine interleukin-26 targets epithelial cells through the interleukin-20 receptor 1 and interleukin-10 receptor 2 chains.40
202374962010New genetic associations detected in a host response study to hepatitis B vaccine.27
192589232009Genetic susceptibility to respiratory syncytial virus bronchiolitis in preterm children is associated with airway remodeling genes and innate immune genes.26
237049222013IL-26 promotes the proliferation and survival of human gastric cancer cells by regulating the balance of STAT1 and STAT3 activation.20
283563842017IL-26 Confers Proinflammatory Properties to Extracellular DNA.18

Citation

Dessen P

IL26 (interleukin 26)

Atlas Genet Cytogenet Oncol Haematol. 2014-01-01

Online version: http://atlasgeneticsoncology.org/gene/53680/il26