Identity
HGNC
LOCATION
Xq13.1
LOCUSID
ALIAS
CD132,CIDX,IL-2RG,IMD4,P64,SCIDX,SCIDX1
FUSION GENES
Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 3561
MIM: 308380
HGNC: 6010
Ensembl: ENSG00000147168
Variants:
dbSNP: 3561
ClinVar: 3561
TCGA: ENSG00000147168
COSMIC: IL2RG
RNA/Proteins
Expression (GTEx)
Pathways
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 38720389 | 2024 | IL-2RG as a possible immunotherapeutic target in CRC predicting poor prognosis and regulated by miR-7-5p and miR-26b-5p. | 0 |
| 38720389 | 2024 | IL-2RG as a possible immunotherapeutic target in CRC predicting poor prognosis and regulated by miR-7-5p and miR-26b-5p. | 0 |
| 36645024 | 2023 | Keratinocytes activated by IL-4/IL-13 express IL-2Rγ with consequences on epidermal barrier function. | 2 |
| 37481508 | 2023 | Somatic Genetic Reversion of a Duplication Event in IL2RG in Siblings. | 0 |
| 37904191 | 2023 | NFAT1 and NFκB regulates expression of the common γ-chain cytokine receptor in activated T cells. | 0 |
| 37932447 | 2023 | PD-1 signaling negatively regulates the common cytokine receptor γ chain via MARCH5-mediated ubiquitination and degradation to suppress anti-tumor immunity. | 3 |
| 36645024 | 2023 | Keratinocytes activated by IL-4/IL-13 express IL-2Rγ with consequences on epidermal barrier function. | 2 |
| 37481508 | 2023 | Somatic Genetic Reversion of a Duplication Event in IL2RG in Siblings. | 0 |
| 37904191 | 2023 | NFAT1 and NFκB regulates expression of the common γ-chain cytokine receptor in activated T cells. | 0 |
| 37932447 | 2023 | PD-1 signaling negatively regulates the common cytokine receptor γ chain via MARCH5-mediated ubiquitination and degradation to suppress anti-tumor immunity. | 3 |
| 33959125 | 2021 | Case Report: A Novel IL2RG Frame-Restoring Rescue Mutation Mimics Early T Cell Engraftment Following Haploidentical Hematopoietic Stem Cell Transplantation in a Patient With X-SCID. | 0 |
| 34382351 | 2021 | Survival-Assured Liver Injury Preconditioning (SALIC) Enables Robust Expansion of Human Hepatocytes in Fah(-/-) Rag2(-/-) IL2rg(-/-) Rats. | 4 |
| 35052377 | 2021 | Somatic Reversion of a Novel IL2RG Mutation Resulting in Atypical X-Linked Combined Immunodeficiency. | 6 |
| 33959125 | 2021 | Case Report: A Novel IL2RG Frame-Restoring Rescue Mutation Mimics Early T Cell Engraftment Following Haploidentical Hematopoietic Stem Cell Transplantation in a Patient With X-SCID. | 0 |
| 34382351 | 2021 | Survival-Assured Liver Injury Preconditioning (SALIC) Enables Robust Expansion of Human Hepatocytes in Fah(-/-) Rag2(-/-) IL2rg(-/-) Rats. | 4 |
Citation
Dessen P
IL2RG (interleukin 2 receptor subunit gamma)
Atlas Genet Cytogenet Oncol Haematol. 2007-02-01
Online version: http://atlasgeneticsoncology.org/gene/46194/il2rg
