Identity
HGNC
LOCATION
16p13.3
LOCUSID
ALIAS
IL-32alpha,IL-32beta,IL-32delta,IL-32gamma,NK4,TAIF,TAIFa,TAIFb,TAIFc,TAIFd
FUSION GENES
Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 9235
MIM: 606001
HGNC: 16830
Ensembl: ENSG00000008517
Variants:
dbSNP: 9235
ClinVar: 9235
TCGA: ENSG00000008517
COSMIC: IL32
RNA/Proteins
Expression (GTEx)
Pathways
| Pathway | Source | External ID |
|---|---|---|
| Immune System | REACTOME | R-HSA-168256 |
| Cytokine Signaling in Immune system | REACTOME | R-HSA-1280215 |
| Signaling by Interleukins | REACTOME | R-HSA-449147 |
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 37658685 | 2024 | Modulatory effects of point-mutated IL-32θ (A94V) on tumor progression in triple-negative breast cancer cells. | 2 |
| 38232700 | 2024 | IL32 downregulation lowers triglycerides and type I collagen in di-lineage human primary liver organoids. | 0 |
| 38316697 | 2024 | IL-32 production from lung adenocarcinoma cells is potentially involved in immunosuppressive microenvironment. | 0 |
| 37658685 | 2024 | Modulatory effects of point-mutated IL-32θ (A94V) on tumor progression in triple-negative breast cancer cells. | 2 |
| 38232700 | 2024 | IL32 downregulation lowers triglycerides and type I collagen in di-lineage human primary liver organoids. | 0 |
| 38316697 | 2024 | IL-32 production from lung adenocarcinoma cells is potentially involved in immunosuppressive microenvironment. | 0 |
| 36516653 | 2023 | Diverse and divergent functions of IL-32β and IL-32γ isoforms in the regulation of malignant pleural mesothelioma cell growth and the production of VEGF-A and CXCL8. | 0 |
| 36602425 | 2023 | Impacts of IL-27 and IL-32 in the pathogenesis and outcome of COVID-19 associated mucormycosis. | 1 |
| 36992409 | 2023 | Differential Impact of IL-32 Isoforms on the Functions of Coronary Artery Endothelial Cells: A Potential Link with Arterial Stiffness and Atherosclerosis. | 1 |
| 37105370 | 2023 | IL-32 and its paradoxical role in neoplasia. | 1 |
| 37228610 | 2023 | Human IL-32θA94V mutant attenuates monocyte-endothelial adhesion by suppressing the expression of ICAM-1 and VCAM-1 via binding to cell surface receptor integrin αVβ3 and αVβ6 in TNF-α-stimulated HUVECs. | 3 |
| 37261903 | 2023 | Hepatic interleukin 32 attenuates liver injury through repression of necroptosis in cholestasis. | 0 |
| 37396740 | 2023 | Estimation of Interleukin 32 and Interleukin 37 Serum Levels in Iraqi Patients with Rheumatoid Arthritis. | 1 |
| 37686029 | 2023 | Saturated Fat-Mediated Upregulation of IL-32 and CCL20 in Hepatocytes Contributes to Higher Expression of These Fibrosis-Driving Molecules in MASLD. | 3 |
| 36516653 | 2023 | Diverse and divergent functions of IL-32β and IL-32γ isoforms in the regulation of malignant pleural mesothelioma cell growth and the production of VEGF-A and CXCL8. | 0 |
Citation
Dessen P
IL32 (interleukin 32)
Atlas Genet Cytogenet Oncol Haematol. 2008-05-01
Online version: http://atlasgeneticsoncology.org/gene/50130/il32
