Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 3565
MIM: 147780
HGNC: 6014
Ensembl: ENSG00000113520
Variants:
dbSNP: 3565
ClinVar: 3565
TCGA: ENSG00000113520
COSMIC: IL4
RNA/Proteins
Expression (GTEx)
Pathways
Protein levels (Protein atlas)
PharmGKB
| Entity ID | Name | Type | Evidence | Association | PK | PD | PMIDs |
|---|---|---|---|---|---|---|---|
| PA443450 | Asthma | Disease | ClinicalAnnotation | associated | PD | 20921925 | |
| PA448497 | aspirin | Chemical | ClinicalAnnotation | associated | PD | 20921925 |
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 37803493 | 2024 | Association of MIF-173G/C, IL-4 VNTR, and IL-1RA VNTR variants with FMF-related amyloidosis in a Turkish cohort. | 0 |
| 38057662 | 2024 | An IL-4 signalling axis in bone marrow drives pro-tumorigenic myelopoiesis. | 11 |
| 38135009 | 2024 | IgE and anaphylaxis specific to the carbohydrate alpha-gal depend on IL-4. | 1 |
| 38146141 | 2024 | Interleukin-4 and Interleukin-17 are associated with coronary artery disease. | 1 |
| 38147125 | 2024 | IL-4-secreting CD40L(+) MAIT cells support antibody production in the peripheral blood of Heonch-Schönlein purpura patients. | 0 |
| 38155071 | 2024 | Expression of miR-21 &IL-4 in endometriosis. | 0 |
| 38206766 | 2024 | Linking adipose tissue eosinophils, IL-4, and leptin in human obesity and insulin resistance. | 1 |
| 38238514 | 2024 | Evaluation of serum interleukin-12 and interleukin-4 as potential biomarkers for the diagnosis of major depressive disorder. | 1 |
| 38497343 | 2024 | The association of 25(OH)D, interleukin-4, interleukin-5, and interleukin-13 levels with the burden of soil-transmitted helminth infection in stunted children aged 24-59 months. | 0 |
| 38649353 | 2024 | PD-L1- and IL-4-expressing basophils promote pathogenic accumulation of T follicular helper cells in lupus. | 0 |
| 38690818 | 2024 | Association of IL-4 polymorphism with severe periodontitis in a sample of Iraqi population. | 0 |
| 37803493 | 2024 | Association of MIF-173G/C, IL-4 VNTR, and IL-1RA VNTR variants with FMF-related amyloidosis in a Turkish cohort. | 0 |
| 38057662 | 2024 | An IL-4 signalling axis in bone marrow drives pro-tumorigenic myelopoiesis. | 11 |
| 38135009 | 2024 | IgE and anaphylaxis specific to the carbohydrate alpha-gal depend on IL-4. | 1 |
| 38146141 | 2024 | Interleukin-4 and Interleukin-17 are associated with coronary artery disease. | 1 |
Citation
Dessen P
IL4 (interleukin 4)
Atlas Genet Cytogenet Oncol Haematol. 2003-11-01
Online version: http://atlasgeneticsoncology.org/gene/40960/il4
