Identity
HGNC
LOCATION
5q11.2
LOCUSID
ALIAS
CD130,CDW130,GP130,HIES4,IL-6RB,sGP130
FUSION GENES
Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 3572
MIM: 600694
HGNC: 6021
Ensembl: ENSG00000134352
Variants:
dbSNP: 3572
ClinVar: 3572
TCGA: ENSG00000134352
COSMIC: IL6ST
RNA/Proteins
Expression (GTEx)
Pathways
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 38453915 | 2024 | Structural insights into IL-11-mediated signalling and human IL6ST variant-associated immunodeficiency. | 0 |
| 38578568 | 2024 | An Indian Family with Autosomal Dominant Hyper-IgE Syndrome Due to IL6ST Defect. | 0 |
| 38615236 | 2024 | Association of serum IL-30 and soluble GP130 with the risk of psoriasis vulgaris. | 0 |
| 38453915 | 2024 | Structural insights into IL-11-mediated signalling and human IL6ST variant-associated immunodeficiency. | 0 |
| 38578568 | 2024 | An Indian Family with Autosomal Dominant Hyper-IgE Syndrome Due to IL6ST Defect. | 0 |
| 38615236 | 2024 | Association of serum IL-30 and soluble GP130 with the risk of psoriasis vulgaris. | 0 |
| 35435804 | 2023 | Impaired degradation of YAP1 and IL6ST by chaperone-mediated autophagy promotes proliferation and migration of normal and hepatocellular carcinoma cells. | 12 |
| 36565897 | 2023 | Variation in IL6ST cytokine family function and the potential of IL6 trans-signalling in ERα positive breast cancer cells. | 1 |
| 37098986 | 2023 | Decreased Serum Levels of Soluble Oncostatin M Receptor (sOSMR) and Glycoprotein 130 (sgp130) in Patients with Coronary Artery Disease. | 2 |
| 37243282 | 2023 | Association of Polymorphisms of IL-6 Pathway Genes (IL6, IL6R and IL6ST) with COVID-19 Severity in an Amazonian Population. | 2 |
| 37820452 | 2023 | Biophysical insight into protein-protein interactions in the Interleukin-11/Interleukin-11Rα/glycoprotein 130 signaling complex. | 0 |
| 37828513 | 2023 | Associations between serum estradiol and IL-6/sIL-6R/sgp130 complex in female patients with major depressive disorder. | 0 |
| 37880158 | 2023 | Mononuclear cells from patients with rhupus are influenced by TNF in their production of gp130/sIL-6Rb and APRIL. | 0 |
| 38133879 | 2023 | The Human GP130 Cytokine Receptor and Its Expression-an Atlas and Functional Taxonomy of Genetic Variants. | 1 |
| 35435804 | 2023 | Impaired degradation of YAP1 and IL6ST by chaperone-mediated autophagy promotes proliferation and migration of normal and hepatocellular carcinoma cells. | 12 |
Citation
Dessen P
IL6ST (interleukin 6 cytokine family signal transducer)
Atlas Genet Cytogenet Oncol Haematol. 2003-08-01
Online version: http://atlasgeneticsoncology.org/gene/40964/il6st
