IMPACT (impact RWD domain protein)

2014-11-01  

Identity

HGNC
IMPACT
LOCATION
18q11.2
LOCUSID
55364
ALIAS
RWDD5
FUSION GENES
Show Gene Fusions

Other Information

Locus ID:

NCBI: 55364
MIM: 615319
HGNC: 20387
Ensembl: ENSG00000154059

Variants:

dbSNP: 55364
ClinVar: 55364
TCGA: ENSG00000154059
COSMIC: IMPACT

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000154059ENST00000284202Q9P2X3
ENSG00000154059ENST00000578221J3QRS6
ENSG00000154059ENST00000580035J3QLU6
ENSG00000154059ENST00000581278J3QQU0
ENSG00000154059ENST00000585067J3KT25
ENSG00000154059ENST00000648078A0A3B3ITH3

Expression (GTEx)

0
5
10
15
20
25
30
35
40
Adipose - Subcutaneous
Adipose - Visceral
Adrenal Gland
Artery - Aorta
Artery - Tibial
Bladder
Brain - Amygdala
Brain - Anterior cingulate cortex
Brain - Caudate
Brain - Cerebellar Hemisphere
Brain - Cerebellum
Brain - Cortex
Brain - Frontal Cortex
Brain - Hippocampus
Brain - Hypothalamus
Brain - Nucleus accumbens
Brain - Putamen
Brain - Spinal cord
Brain - Substantia nigra
Breast - Mammary Tissue
Cells - Cultured fibroblasts
Cells - EBV - transformed lymphocytes
Cervix - Ectocervix
Cervix - Endocervix
Colon - Sigmoid
Colon - Transverse
Esophagus - Gastroesophageal Junction
Esophagus - Mucosa
Esophagus - Muscularis
Fallopian Tube
Heart - Atrial Appendage
Heart - Left Ventricle
Kidney - Cortex
Kidney - Medulla
Liver
Lung
Minor Salivary Gland
Muscle - Skeletal
Nerve - Tibial
Ovary
Pancreas
Pituitary
Prostate
Skin - Not Sun Exposed
Skin - Sun Exposed
Small Intestine - Terminal Ileum
Spleen
Stomach
Testis
Thyroid
Uterus
Vagina
Whole Blood

Protein levels (Protein atlas)

Not detected
Low
Medium
High
cerebral cortex
cerebellum
hippocampus
caudate
thyroid gland
parathyroid gland
adrenal gland
nasopharynx
bronchus
lung
oral mucosa
salivary gland
esophagus
stomach 1
stomach 2
duodenum
small intestine
colon
rectum
liver
gallbladder
pancreas
kidney
urinary bladder
testis
epididymis
seminal vesicle
prostate
vagina
ovary
fallopian tube
endometrium 1
endometrium 2
cervix, uterine
placenta
breast
heart muscle
smooth muscle
skeletal muscle
soft tissue 1
soft tissue 2
adipose tissue
skin 1
skin 2
appendix
spleen
lymph node
tonsil
bone marrow

References

Pubmed IDYearTitleCitations
202374962010New genetic associations detected in a host response study to hepatitis B vaccine.27
206486302010High expression of IMPACT protein promotes resistance to indoleamine 2,3-dioxygenase-induced cell death.6
157527302005Comparative genomics approach toward critical determinants for the imprinting of an evolutionarily conserved gene Impact.3
158714612004An evolutionary scenario for genomic imprinting of Impact lying between nonimprinted neighbors.3

Citation

Dessen P

IMPACT (impact RWD domain protein)

Atlas Genet Cytogenet Oncol Haematol. 2014-11-01

Online version: http://atlasgeneticsoncology.org/gene/64610/impact