INA (internexin neuronal intermediate filament protein alpha)

2008-09-01  

Identity

HGNC
LOCATION
10q24.33
LOCUSID
ALIAS
NEF5,NF-66,TXBP-1
FUSION GENES

Other Information

Locus ID:

NCBI: 9118
MIM: 605338
HGNC: 6057
Ensembl: ENSG00000148798

Variants:

dbSNP: 9118
ClinVar: 9118
TCGA: ENSG00000148798
COSMIC: INA

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000148798ENST00000369849Q16352

Expression (GTEx)

0
50
100
150
200

Protein levels (Protein atlas)

Not detected
Low
Medium
High

References

Pubmed IDYearTitleCitations
163854512006A scan of chromosome 10 identifies a novel locus showing strong association with late-onset Alzheimer disease.69
191102652009Proteomic analysis of dorsolateral prefrontal cortex indicates the involvement of cytoskeleton, oligodendrocyte, energy metabolism and new potential markers in schizophrenia.43
151616492004alpha-internexin is present in the pathological inclusions of neuronal intermediate filament inclusion disease.36
219900412012The clinical implications and biologic relevance of neurofilament expression in gastroenteropancreatic neuroendocrine neoplasms.9
244831522014α-Internexin: a novel biomarker for pancreatic neuroendocrine tumor aggressiveness.9
202133202010How the projection domains of NF-L and alpha-internexin determine the conformations of NF-M and NF-H in neurofilaments.7
228909692012Molecular genetics of adult grade II gliomas: towards a comprehensive tumor classification system.7
167229802006Topography of alpha-internexin-positive neuronal aggregates in 10 patients with neuronal intermediate filament inclusion disease.6
191393672009alpha-Internexin expression identifies 1p19q codeleted gliomas.5
262335222015Coexpression of cyclin D1 and alpha-internexin in oligodendroglial tumors.4

Citation

Dessen P

INA (internexin neuronal intermediate filament protein alpha)

Atlas Genet Cytogenet Oncol Haematol. 2008-09-01

Online version: http://atlasgeneticsoncology.org/gene/50337/ina