INHBB (inhibin subunit beta B)

2003-06-01  

Identity

HGNC
LOCATION
2q14.2
LOCUSID
ALIAS
-

Other Information

Locus ID:

NCBI: 3625
MIM: 147390
HGNC: 6067
Ensembl: ENSG00000163083

Variants:

dbSNP: 3625
ClinVar: 3625
TCGA: ENSG00000163083
COSMIC: INHBB

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000163083ENST00000295228P09529

Expression (GTEx)

0
10
20
30
40
50
60
70
80
90
100

Pathways

PathwaySourceExternal ID
Cytokine-cytokine receptor interactionKEGGko04060
TGF-beta signaling pathwayKEGGko04350
Cytokine-cytokine receptor interactionKEGGhsa04060
TGF-beta signaling pathwayKEGGhsa04350
Signaling pathways regulating pluripotency of stem cellsKEGGhsa04550
Signaling pathways regulating pluripotency of stem cellsKEGGko04550
Activin signalingKEGGhsa_M00681
Activin signalingKEGGM00681
Metabolism of proteinsREACTOMER-HSA-392499
Peptide hormone metabolismREACTOMER-HSA-2980736
Peptide hormone biosynthesisREACTOMER-HSA-209952
Glycoprotein hormonesREACTOMER-HSA-209822
Signal TransductionREACTOMER-HSA-162582
Signaling by ActivinREACTOMER-HSA-1502540
Antagonism of Activin by FollistatinREACTOMER-HSA-2473224

References

Pubmed IDYearTitleCitations
185937672008Anti-mullerian hormone and inhibin B in the definition of ovarian aging and the menopause transition.83
176665952007Symptoms associated with menopausal transition and reproductive hormones in midlife women.77
226111572012Induction of activin B by inflammatory stimuli up-regulates expression of the iron-regulatory peptide hepcidin through Smad1/5/8 signaling.72
189272372008Proteomic identification and functional validation of activins and bone morphogenetic protein 11 as candidate novel muscle mass regulators.58
243788732014Elevated expression of activins promotes muscle wasting and cachexia.46
202003322010Family-based analysis of candidate genes for polycystic ovary syndrome.40
207340642010A large-scale candidate gene association study of age at menarche and age at natural menopause.38
206341972010Comprehensive analysis of common genetic variation in 61 genes related to steroid hormone and insulin-like growth factor-I metabolism and breast cancer risk in the NCI breast and prostate cancer cohort consortium.25
224320412012Genome-wide association scan identifies a risk locus for preeclampsia on 2q14, near the inhibin, beta B gene.24
169353892006Deregulation of the activin/follistatin system in hepatocarcinogenesis.22

Citation

Dessen P

INHBB (inhibin subunit beta B)

Atlas Genet Cytogenet Oncol Haematol. 2003-06-01

Online version: http://atlasgeneticsoncology.org/gene/40981/inhbb