Atlas of Genetics and Cytogenetics in Oncology and Haematology

Home   Genes   Leukemias   Solid Tumours   Cancer-Prone   Deep Insight   Case Reports   Journals  Portal   Teaching   
X Y 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 NA

INSRR (insulin receptor-related receptor)

Identity

Other namesIRR
HGNC (Hugo) INSRR
LocusID (NCBI) 3645
Location 1q23.1
Location_base_pair Starts at 156810665 and ends at 156828712 bp from pter ( according to hg19-Feb_2009)
Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 

External links

Nomenclature
HGNC (Hugo)INSRR   6093
Entrez_Gene (NCBI)INSRR  3645  insulin receptor-related receptor
Cards
GeneCards (Weizmann)INSRR
Ensembl (Hinxton)ENSG00000027644 [Gene_View]  chr1:156810665-156828712 [Contig_View]  INSRR [Vega]
AceView (NCBI)INSRR
Genatlas (Paris)INSRR
SOURCE (Stanford)NM_014215
Genomic and cartography
GoldenPath (UCSC)INSRR  -  1q23.1   chr1:156810665-156828712 -  1q23.1   [Description]    (hg19-Feb_2009)
EnsemblINSRR - 1q23.1 [CytoView]
Mapping of homologs : NCBIINSRR [Mapview]
OMIM147671   
Gene and transcription
Genbank (Entrez)AF064078 AK310760 BC156081 BC157044 J05046
RefSeq transcript (SRS)NM_014215
RefSeq transcript (Entrez)NM_014215
RefSeq genomic (SRS)AC_000133 NC_000001 NC_018912 NG_007493 NT_004487 NW_001838531 NW_004077999
RefSeq genomic (Entrez)AC_000133 NC_000001 NC_018912 NG_007493 NT_004487 NW_001838531 NW_004077999
Consensus coding sequences : CCDS (NCBI)INSRR
Cluster EST : UnigeneHs.248138 [ SRS ] Hs.248138 [ NCBI ]
CGAP (NCI)Hs.248138
Alternative Splicing : Fast-db (Paris)GSHG0002621
Alternative Splicing GalleryENSG00000027644
Gene ExpressionINSRR [ NCBI-GEO ]   INSRR [ EBI - ARRAY_EXPRESS ]
Protein : pattern, domain, 3D structure
UniProt/SwissProtP14616 (SRS) P14616 (Uniprot)
NextProtP14616
With graphics : InterProP14616
Splice isoforms : SwissVarP14616(Swissvar)
Domaine pattern : Prosite (SRS)FN3 (PS50853)    PROTEIN_KINASE_ATP (PS00107)    PROTEIN_KINASE_DOM (PS50011)    PROTEIN_KINASE_TYR (PS00109)    RECEPTOR_TYR_KIN_II (PS00239)   
Domaine pattern : Prosite (Expaxy)FN3 (PS50853)    PROTEIN_KINASE_ATP (PS00107)    PROTEIN_KINASE_DOM (PS50011)    PROTEIN_KINASE_TYR (PS00109)    RECEPTOR_TYR_KIN_II (PS00239)   
Domains : Interpro (SRS)EGF_rcpt_L    Fibronectin_type3    Furin-like_Cys-rich_dom    Furin_repeat    Growth_fac_rcpt    Ig-like_fold    Kinase-like_dom    Prot_kinase_cat_dom    Protein_kinase_ATP_BS    Ser-Thr/Tyr_kinase_cat_dom    Tyr_kinase_AS    Tyr_kinase_cat_dom    Tyr_kinase_insulin-like_rcpt    Tyr_kinase_rcpt_2_CS   
Domains : Interpro (EBI)EGF_rcpt_L    Fibronectin_type3    Furin-like_Cys-rich_dom    Furin_repeat    Growth_fac_rcpt    Ig-like_fold    Kinase-like_dom    Prot_kinase_cat_dom    Protein_kinase_ATP_BS    Ser-Thr/Tyr_kinase_cat_dom    Tyr_kinase_AS    Tyr_kinase_cat_dom    Tyr_kinase_insulin-like_rcpt    Tyr_kinase_rcpt_2_CS   
Related proteins : CluSTrP14616
Domain families : Pfam (SRS)fn3 (PF00041)    Furin-like (PF00757)    Pkinase_Tyr (PF07714)    Recep_L_domain (PF01030)   
Domain families : Pfam (Sanger)fn3 (PF00041)    Furin-like (PF00757)    Pkinase_Tyr (PF07714)    Recep_L_domain (PF01030)   
Domain families : Pfam (NCBI)pfam00041    pfam00757    pfam07714    pfam01030   
Domain families : Smart (EMBL)FN3 (SM00060)  FU (SM00261)  TyrKc (SM00219)  
DMDM3645
Blocks (Seattle)P14616
Human Protein AtlasENSG00000027644
HPRD00976
IPIIPI00027212   
Protein Interaction databases
DIP (DOE-UCLA)P14616
IntAct (EBI)P14616
FunCoupENSG00000027644
REACTOMEINSRR
Protein Interaction Database3645
BioGRIDINSRR
InParanoidP14616
Interologous Interaction database P14616
IntegromeDBINSRR
Polymorphism : SNP, mutations, diseases
SNP Single Nucleotide Polymorphism (NCBI)INSRR
SNP (GeneSNP Utah)INSRR
SNP : HGBaseINSRR
Genetic variants : HAPMAPINSRR
Somatic Mutations in Cancer : COSMICINSRR 
CONAN: Copy Number AnalysisINSRR 
Mutations and Diseases : HGMDINSRR
OMIM147671   
GENETests147671   
Disease Genetic AssociationINSRR
Huge Navigator INSRR [HugePedia]  INSRR [HugeCancerGEM]
Genomic VariantsINSRR  INSRR [DGVbeta]
snp3D : Map Gene to Disease3645
General knowledge
Homologs : HomoloGeneINSRR
Homology/Alignments : Family Browser (UCSC)INSRR
Phylogenetic Trees/Animal Genes : TreeFamINSRR
Catalytic activity : Enzyme2.7.10.1 [ Enzyme-Expasy ]   2.7.10.1 [ Enzyme-SRS ]   2.7.10.1 [ IntEnz-EBI ]   2.7.10.1 [ BRENDA ]   2.7.10.1 [ KEGG ]   
Chemical/Protein Interactions : CTD3645
Chemical/Pharm GKB GenePA29899
Clinical trialINSRR
Cancer Resource (Charite)ENSG00000027644
Ontology : AmiGOtransmembrane receptor protein tyrosine kinase activity  transmembrane receptor protein tyrosine kinase activity  ATP binding  integral to plasma membrane  transmembrane receptor protein tyrosine kinase signaling pathway  male sex determination  actin cytoskeleton reorganization  phosphatidylinositol 3-kinase binding  insulin receptor substrate binding  protein autophosphorylation  cellular response to alkalinity  
Ontology : EGO-EBItransmembrane receptor protein tyrosine kinase activity  transmembrane receptor protein tyrosine kinase activity  ATP binding  integral to plasma membrane  transmembrane receptor protein tyrosine kinase signaling pathway  male sex determination  actin cytoskeleton reorganization  phosphatidylinositol 3-kinase binding  insulin receptor substrate binding  protein autophosphorylation  cellular response to alkalinity  
Other databases
Probes
Litterature
PubMed15 Pubmed reference(s) in Entrez
PubGeneINSRR
iHOPINSRR
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

Search in all EBI   NCBI

Contributor(s)

Written09-2002Dessen P, Le Minor S
Updated01-2013Dessen P

© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Wed May 1 12:46:36 CEST 2013
Home   Genes   Leukemias   Solid Tumours   Cancer-Prone   Deep Insight   Case Reports   Journals  Portal   Teaching   

For comments and suggestions or contributions, please contact us

jlhuret@AtlasGeneticsOncology.org.