INTS10 (integrator complex subunit 10)

2017-08-01  

Identity

HGNC
INTS10
LOCATION
8p21.3
LOCUSID
55174
ALIAS
C8orf35,INT10
FUSION GENES
Show Gene Fusions

Other Information

Locus ID:

NCBI: 55174
MIM: 611353
HGNC: 25548
Ensembl: ENSG00000104613

Variants:

dbSNP: 55174
ClinVar: 55174
TCGA: ENSG00000104613
COSMIC: INTS10

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000104613ENST00000397977Q9NVR2
ENSG00000104613ENST00000518424E5RJN5
ENSG00000104613ENST00000518799H0YBH6
ENSG00000104613ENST00000520670H0YBB0
ENSG00000104613ENST00000520827H0YB48
ENSG00000104613ENST00000521008H0YAY7
ENSG00000104613ENST00000521357H0YC09
ENSG00000104613ENST00000522114E5RHN1
ENSG00000104613ENST00000523772H0YB36
ENSG00000104613ENST00000523846H0YBW3
ENSG00000104613ENST00000523869H0YAU7

Expression (GTEx)

0
10
20
30
40
50
60
70
Adipose - Subcutaneous
Adipose - Visceral
Adrenal Gland
Artery - Aorta
Artery - Tibial
Bladder
Brain - Amygdala
Brain - Anterior cingulate cortex
Brain - Caudate
Brain - Cerebellar Hemisphere
Brain - Cerebellum
Brain - Cortex
Brain - Frontal Cortex
Brain - Hippocampus
Brain - Hypothalamus
Brain - Nucleus accumbens
Brain - Putamen
Brain - Spinal cord
Brain - Substantia nigra
Breast - Mammary Tissue
Cells - Cultured fibroblasts
Cells - EBV - transformed lymphocytes
Cervix - Ectocervix
Cervix - Endocervix
Colon - Sigmoid
Colon - Transverse
Esophagus - Gastroesophageal Junction
Esophagus - Mucosa
Esophagus - Muscularis
Fallopian Tube
Heart - Atrial Appendage
Heart - Left Ventricle
Kidney - Cortex
Kidney - Medulla
Liver
Lung
Minor Salivary Gland
Muscle - Skeletal
Nerve - Tibial
Ovary
Pancreas
Pituitary
Prostate
Skin - Not Sun Exposed
Skin - Sun Exposed
Small Intestine - Terminal Ileum
Spleen
Stomach
Testis
Thyroid
Uterus
Vagina
Whole Blood

Pathways

PathwaySourceExternal ID
Gene ExpressionREACTOMER-HSA-74160
RNA polymerase II transcribes snRNA genesREACTOMER-HSA-6807505

Protein levels (Protein atlas)

Not detected
Low
Medium
High
cerebral cortex
cerebellum
hippocampus
caudate
thyroid gland
parathyroid gland
adrenal gland
nasopharynx
bronchus
lung
oral mucosa
salivary gland
esophagus
stomach 1
stomach 2
duodenum
small intestine
colon
rectum
liver
gallbladder
pancreas
kidney
urinary bladder
testis
epididymis
seminal vesicle
prostate
vagina
ovary
fallopian tube
endometrium 1
endometrium 2
cervix, uterine
placenta
breast
heart muscle
smooth muscle
skeletal muscle
soft tissue 1
soft tissue 2
adipose tissue
skin 1
skin 2
appendix
spleen
lymph node
tonsil
bone marrow

References

Pubmed IDYearTitleCitations
272445552016Genome-wide association study identifies 8p21.3 associated with persistent hepatitis B virus infection among Chinese.14
280273112016Somatic Mutation Patterns in Hemizygous Genomic Regions Unveil Purifying Selection during Tumor Evolution.4

Citation

Dessen P

INTS10 (integrator complex subunit 10)

Atlas Genet Cytogenet Oncol Haematol. 2017-08-01

Online version: http://atlasgeneticsoncology.org/gene/56972/ints10