IRAK1BP1 (interleukin 1 receptor associated kinase 1 binding protein 1)

2014-11-01  

Identity

HGNC
IRAK1BP1
LOCATION
6q14.1
LOCUSID
134728
ALIAS
AIP70,SIMPL
FUSION GENES
Show Gene Fusions

Other Information

Locus ID:

NCBI: 134728
MIM: 615375
HGNC: 17368
Ensembl: ENSG00000146243

Variants:

dbSNP: 134728
ClinVar: 134728
TCGA: ENSG00000146243
COSMIC: IRAK1BP1

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000146243ENST00000369940Q5VVH5
ENSG00000146243ENST00000606868U3KQ57
ENSG00000146243ENST00000606929U3KQ00
ENSG00000146243ENST00000607739U3KQ34

Expression (GTEx)

0
1
2
3
4
5
6
Adipose - Subcutaneous
Adipose - Visceral
Adrenal Gland
Artery - Aorta
Artery - Tibial
Bladder
Brain - Amygdala
Brain - Anterior cingulate cortex
Brain - Caudate
Brain - Cerebellar Hemisphere
Brain - Cerebellum
Brain - Cortex
Brain - Frontal Cortex
Brain - Hippocampus
Brain - Hypothalamus
Brain - Nucleus accumbens
Brain - Putamen
Brain - Spinal cord
Brain - Substantia nigra
Breast - Mammary Tissue
Cells - Cultured fibroblasts
Cells - EBV - transformed lymphocytes
Cervix - Ectocervix
Cervix - Endocervix
Colon - Sigmoid
Colon - Transverse
Esophagus - Gastroesophageal Junction
Esophagus - Mucosa
Esophagus - Muscularis
Fallopian Tube
Heart - Atrial Appendage
Heart - Left Ventricle
Kidney - Cortex
Kidney - Medulla
Liver
Lung
Minor Salivary Gland
Muscle - Skeletal
Nerve - Tibial
Ovary
Pancreas
Pituitary
Prostate
Skin - Not Sun Exposed
Skin - Sun Exposed
Small Intestine - Terminal Ileum
Spleen
Stomach
Testis
Thyroid
Uterus
Vagina
Whole Blood

Protein levels (Protein atlas)

Not detected
Low
Medium
High
N/A

References

Pubmed IDYearTitleCitations
170793332007Phosphorylation of SIMPL modulates RelA-associated NF-kappaB-dependent transcription.2

Citation

Dessen P

IRAK1BP1 (interleukin 1 receptor associated kinase 1 binding protein 1)

Atlas Genet Cytogenet Oncol Haematol. 2014-11-01

Online version: http://atlasgeneticsoncology.org/gene/64661/irak1bp1