Identity
HGNC
LOCATION
11p15.5
LOCUSID
ALIAS
IMD39,IRF-7,IRF-7H,IRF7A,IRF7B,IRF7C,IRF7H
FUSION GENES
Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 3665
MIM: 605047
HGNC: 6122
Ensembl: ENSG00000185507
Variants:
dbSNP: 3665
ClinVar: 3665
TCGA: ENSG00000185507
COSMIC: IRF7
RNA/Proteins
Expression (GTEx)
Pathways
Protein levels (Protein atlas)
PharmGKB
| Entity ID | Name | Type | Evidence | Association | PK | PD | PMIDs |
|---|---|---|---|---|---|---|---|
| PA164722208 | MAVS | Gene | Pathway | associated | 26111151 |
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 38508315 | 2024 | Non-transcriptional IRF7 interacts with NF-κB to inhibit viral inflammation. | 0 |
| 38508315 | 2024 | Non-transcriptional IRF7 interacts with NF-κB to inhibit viral inflammation. | 0 |
| 37251373 | 2023 | Interferon regulatory factor 7 in inflammation, cancer and infection. | 17 |
| 37638030 | 2023 | IRF7: role and regulation in immunity and autoimmunity. | 9 |
| 37251373 | 2023 | Interferon regulatory factor 7 in inflammation, cancer and infection. | 17 |
| 37638030 | 2023 | IRF7: role and regulation in immunity and autoimmunity. | 9 |
| 33325089 | 2021 | M2 macrophages contribute to cell proliferation and migration of breast cancer. | 21 |
| 33594613 | 2021 | ERVs-TLR3-IRF axis is linked to myelodysplastic syndrome pathogenesis. | 4 |
| 34127522 | 2021 | Porcine Epidemic Diarrhea Virus Membrane Protein Interacted with IRF7 to Inhibit Type I IFN Production during Viral Infection. | 23 |
| 34389779 | 2021 | Role of interferon regulatory factor 7 in corneal endothelial cells after HSV-1 infection. | 3 |
| 33325089 | 2021 | M2 macrophages contribute to cell proliferation and migration of breast cancer. | 21 |
| 33594613 | 2021 | ERVs-TLR3-IRF axis is linked to myelodysplastic syndrome pathogenesis. | 4 |
| 34127522 | 2021 | Porcine Epidemic Diarrhea Virus Membrane Protein Interacted with IRF7 to Inhibit Type I IFN Production during Viral Infection. | 23 |
| 34389779 | 2021 | Role of interferon regulatory factor 7 in corneal endothelial cells after HSV-1 infection. | 3 |
| 31856677 | 2020 | Downregulation of miR-155-5p facilitates enterovirus 71 replication through suppression of type I IFN response by targeting FOXO3/IRF7 pathway. | 13 |
Citation
Dessen P
IRF7 (interferon regulatory factor 7)
Atlas Genet Cytogenet Oncol Haematol. 2007-02-01
Online version: http://atlasgeneticsoncology.org/gene/43745/irf7
