Identity
HGNC
LOCATION
16q24.1
LOCUSID
ALIAS
H-ICSBP,ICSBP,ICSBP1,IMD32A,IMD32B,IRF-8
FUSION GENES
Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 3394
MIM: 601565
HGNC: 5358
Ensembl: ENSG00000140968
Variants:
dbSNP: 3394
ClinVar: 3394
TCGA: ENSG00000140968
COSMIC: IRF8
RNA/Proteins
Expression (GTEx)
Pathways
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 38481803 | 2024 | WTAP Mediated N6-methyladenosine RNA Modification of ELF3 Drives Cellular Senescence by Upregulating IRF8. | 0 |
| 38481803 | 2024 | WTAP Mediated N6-methyladenosine RNA Modification of ELF3 Drives Cellular Senescence by Upregulating IRF8. | 0 |
| 36672246 | 2023 | IRF8 Regulates Intrinsic Ferroptosis through Repressing p53 Expression to Maintain Tumor Cell Sensitivity to Cytotoxic T Lymphocytes. | 3 |
| 36703005 | 2023 | Intrathymic dendritic cell-biased precursors promote human T cell lineage specification through IRF8-driven transmembrane TNF. | 3 |
| 36959484 | 2023 | Loss of IRF8 inhibits the growth of acute myeloid leukemia cells. | 0 |
| 37508555 | 2023 | Expression of Interferon Regulatory Factor 8 (IRF8) and Its Association with Infections in Dialysis Patients. | 0 |
| 37591714 | 2023 | Circulating IRF8-expressing CD123(+)CD127(+) lymphoid progenitors: key players in human hematopoiesis. | 2 |
| 36672246 | 2023 | IRF8 Regulates Intrinsic Ferroptosis through Repressing p53 Expression to Maintain Tumor Cell Sensitivity to Cytotoxic T Lymphocytes. | 3 |
| 36703005 | 2023 | Intrathymic dendritic cell-biased precursors promote human T cell lineage specification through IRF8-driven transmembrane TNF. | 3 |
| 36959484 | 2023 | Loss of IRF8 inhibits the growth of acute myeloid leukemia cells. | 0 |
| 37508555 | 2023 | Expression of Interferon Regulatory Factor 8 (IRF8) and Its Association with Infections in Dialysis Patients. | 0 |
| 37591714 | 2023 | Circulating IRF8-expressing CD123(+)CD127(+) lymphoid progenitors: key players in human hematopoiesis. | 2 |
| 34331664 | 2022 | IRF4 and IRF8 expression are associated with clinical phenotype and clinico-hematological response to hydroxyurea in essential thrombocythemia. | 2 |
| 34991467 | 2022 | Predicting the targets of IRF8 and NFATc1 during osteoclast differentiation using the machine learning method framework cTAP. | 1 |
| 35085599 | 2022 | Global assessment of IRF8 as a novel cancer biomarker. | 3 |
Citation
Dessen P
IRF8 (interferon regulatory factor 8)
Atlas Genet Cytogenet Oncol Haematol. 2008-05-01
Online version: http://atlasgeneticsoncology.org/gene/50137/irf8
