Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 10265
MIM: 606195
HGNC: 14361
Ensembl: ENSG00000176842
Variants:
dbSNP: 10265
ClinVar: 10265
TCGA: ENSG00000176842
COSMIC: IRX5
RNA/Proteins
| Gene ID | Transcript ID | Uniprot |
|---|---|---|
| ENSG00000176842 | ENST00000320990 | P78411 |
| ENSG00000176842 | ENST00000394636 | P78411 |
| ENSG00000176842 | ENST00000560154 | H0YML8 |
| ENSG00000176842 | ENST00000620085 | A2RRB5 |
Expression (GTEx)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 38666481 | 2024 | IRX5 suppresses osteogenic differentiation of hBMSCs by inhibiting protein synthesis. | 0 |
| 38666481 | 2024 | IRX5 suppresses osteogenic differentiation of hBMSCs by inhibiting protein synthesis. | 0 |
| 35328612 | 2022 | The Hematopoietic TALE-Code Shows Normal Activity of IRX1 in Myeloid Progenitors and Reveals Ectopic Expression of IRX3 and IRX5 in Acute Myeloid Leukemia. | 8 |
| 35328612 | 2022 | The Hematopoietic TALE-Code Shows Normal Activity of IRX1 in Myeloid Progenitors and Reveals Ectopic Expression of IRX3 and IRX5 in Acute Myeloid Leukemia. | 8 |
| 32898233 | 2021 | Human model of IRX5 mutations reveals key role for this transcription factor in ventricular conduction. | 11 |
| 33891002 | 2021 | A duplication on chromosome 16q12 affecting the IRXB gene cluster is associated with autosomal dominant cone dystrophy with early tritanopic color vision defect. | 2 |
| 34083488 | 2021 | Extensive pleiotropism and allelic heterogeneity mediate metabolic effects of IRX3 and IRX5. | 46 |
| 34167624 | 2021 | Iroquois Homeobox 5 Negatively Regulated by miRNA-147 Promotes the Proliferation, Metastasis, and Invasion by Oral Squamous Cell Carcinoma. | 1 |
| 32898233 | 2021 | Human model of IRX5 mutations reveals key role for this transcription factor in ventricular conduction. | 11 |
| 33891002 | 2021 | A duplication on chromosome 16q12 affecting the IRXB gene cluster is associated with autosomal dominant cone dystrophy with early tritanopic color vision defect. | 2 |
| 34083488 | 2021 | Extensive pleiotropism and allelic heterogeneity mediate metabolic effects of IRX3 and IRX5. | 46 |
| 34167624 | 2021 | Iroquois Homeobox 5 Negatively Regulated by miRNA-147 Promotes the Proliferation, Metastasis, and Invasion by Oral Squamous Cell Carcinoma. | 1 |
| 32153043 | 2020 | Transcription factorIRX5 promotes hepatocellular carcinoma proliferation and inhibits apoptosis by regulating the p53 signalling pathway. | 12 |
| 32162364 | 2020 | IRX5 prompts genomic instability in colorectal cancer cells. | 5 |
| 32153043 | 2020 | Transcription factorIRX5 promotes hepatocellular carcinoma proliferation and inhibits apoptosis by regulating the p53 signalling pathway. | 12 |
Citation
Dessen P
IRX5 (iroquois homeobox 5)
Atlas Genet Cytogenet Oncol Haematol. 2008-09-01
Online version: http://atlasgeneticsoncology.org/gene/50378/irx5
