ISM1 (isthmin 1)

2014-11-01  

Identity

HGNC
LOCATION
20p12.1
LOCUSID
ALIAS
C20orf82,ISM,Isthmin,bA149I18.1,dJ1077I2.1
FUSION GENES

Other Information

Locus ID:

NCBI: 140862
MIM: 615793
HGNC: 16213
Ensembl: ENSG00000101230

Variants:

dbSNP: 140862
ClinVar: 140862
TCGA: ENSG00000101230
COSMIC: ISM1

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000101230ENST00000262487B1AKI9

Expression (GTEx)

0
10
20
30
40
50
60
70
80
90
100

References

Pubmed IDYearTitleCitations
215440922011Isthmin exerts pro-survival and death-promoting effect on endothelial cells through alphavbeta5 integrin depending on its physical state.17
249560342014Isthmin 1 is a secreted protein expressed in skin, mucosal tissues, and NK, NKT, and th17 cells.5
291626262018Identification of Isthmin 1 as a Novel Clefting and Craniofacial Patterning Gene in Humans.3
315138912019miR-1307-3p overexpression inhibits cell proliferation and promotes cell apoptosis by targeting ISM1 in colon cancer.2
311716302019ISM1 regulates NODAL signaling and asymmetric organ morphogenesis during development.1

Citation

Dessen P

ISM1 (isthmin 1)

Atlas Genet Cytogenet Oncol Haematol. 2014-11-01

Online version: http://atlasgeneticsoncology.org/gene/64673/ism1