Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 9798
MIM: 616434
HGNC: 28977
Ensembl: ENSG00000182149
Variants:
dbSNP: 9798
ClinVar: 9798
TCGA: ENSG00000182149
COSMIC: IST1
RNA/Proteins
Expression (GTEx)
Pathways
| Pathway | Source | External ID |
|---|---|---|
| Endocytosis | KEGG | ko04144 |
| Endocytosis | KEGG | hsa04144 |
| Immune System | REACTOME | R-HSA-168256 |
| Innate Immune System | REACTOME | R-HSA-168249 |
| Neutrophil degranulation | REACTOME | R-HSA-6798695 |
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 38880167 | 2024 | Cigarette smoking-related OLC1 overexpression associated with poor prognosis in bladder urothelial carcinoma. | 0 |
| 38880167 | 2024 | Cigarette smoking-related OLC1 overexpression associated with poor prognosis in bladder urothelial carcinoma. | 0 |
| 35858336 | 2022 | Friction-driven membrane scission by the human ESCRT-III proteins CHMP1B and IST1. | 9 |
| 35858336 | 2022 | Friction-driven membrane scission by the human ESCRT-III proteins CHMP1B and IST1. | 9 |
| 32251413 | 2020 | Membrane constriction and thinning by sequential ESCRT-III polymerization. | 38 |
| 32251413 | 2020 | Membrane constriction and thinning by sequential ESCRT-III polymerization. | 38 |
| 30110633 | 2018 | Resolving ESCRT-III Spirals at the Intercellular Bridge of Dividing Cells Using 3D STORM. | 44 |
| 30110633 | 2018 | Resolving ESCRT-III Spirals at the Intercellular Bridge of Dividing Cells Using 3D STORM. | 44 |
| 28038462 | 2017 | Nuclear overexpression of the overexpressed in lung cancer 1 predicts worse prognosis in gastric adenocarcinoma. | 0 |
| 28532543 | 2017 | [Overexpression of OLC1 in Lung Squamous Cell Carcinoma Tissues is Associated with Poor Prognosis of Patients]. | 1 |
| 28038462 | 2017 | Nuclear overexpression of the overexpressed in lung cancer 1 predicts worse prognosis in gastric adenocarcinoma. | 0 |
| 28532543 | 2017 | [Overexpression of OLC1 in Lung Squamous Cell Carcinoma Tissues is Associated with Poor Prognosis of Patients]. | 1 |
| 25657007 | 2015 | Distinct mechanisms of recognizing endosomal sorting complex required for transport III (ESCRT-III) protein IST1 by different microtubule interacting and trafficking (MIT) domains. | 26 |
| 26011858 | 2015 | ULK3 regulates cytokinetic abscission by phosphorylating ESCRT-III proteins. | 46 |
| 25657007 | 2015 | Distinct mechanisms of recognizing endosomal sorting complex required for transport III (ESCRT-III) protein IST1 by different microtubule interacting and trafficking (MIT) domains. | 26 |
Citation
Dessen P
IST1 (IST1 factor associated with ESCRT-III)
Atlas Genet Cytogenet Oncol Haematol. 2011-09-01
Online version: http://atlasgeneticsoncology.org/gene/52362/ist1
