Identity
HGNC
LOCATION
12q13.13
LOCUSID
ALIAS
CD49e,FNRA,VLA-5,VLA5A
FUSION GENES
Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 3678
MIM: 135620
HGNC: 6141
Ensembl: ENSG00000161638
Variants:
dbSNP: 3678
ClinVar: 3678
TCGA: ENSG00000161638
COSMIC: ITGA5
RNA/Proteins
| Gene ID | Transcript ID | Uniprot |
|---|---|---|
| ENSG00000161638 | ENST00000293379 | P08648 |
| ENSG00000161638 | ENST00000435631 | B4E3F4 |
| ENSG00000161638 | ENST00000547197 | H0YIV7 |
| ENSG00000161638 | ENST00000553071 | H0YHL9 |
Expression (GTEx)
Pathways
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 37144848 | 2024 | TLN1 synergizes with ITGA5 to ameliorate cardiac microvascular endothelial cell dysfunction. | 2 |
| 38160360 | 2024 | A Continuous Extension of Gene Set Enrichment Analysis Using the Likelihood Ratio Test Statistics Identifies Vascular Endothelial Growth Factor as a Candidate Pathway for Alzheimer's Disease via ITGA5. | 0 |
| 38184221 | 2024 | DPP-4 exacerbates LPS-induced endothelial cells inflammation via integrin-α5β1/FAK/AKT signaling. | 0 |
| 38312030 | 2024 | CircRSU1 alleviates LPS-induced human pulmonary microvascular endothelial cell injury by targeting miR-1224-5p/ITGA5 axis. | 0 |
| 38429832 | 2024 | Integrin α5 regulates motility of human monocyte-derived Langerhans cells during immune response. | 0 |
| 38760287 | 2024 | Relationship between aggressive features of oral squamous cell carcinoma and the immunoexpression of CX3CR1, CX3CL1 and ITGAV. | 0 |
| 38830562 | 2024 | hsa_circ_0000518 stimulates the malignant progression of hepatocellular carcinoma via regulating ITGA5 to activate the Warburg effect. | 0 |
| 38918360 | 2024 | IGFBP2/ITGA5 promotes gefitinib resistance via activating STAT3/CXCL1 axis in non-small cell lung cancer. | 0 |
| 37144848 | 2024 | TLN1 synergizes with ITGA5 to ameliorate cardiac microvascular endothelial cell dysfunction. | 2 |
| 38160360 | 2024 | A Continuous Extension of Gene Set Enrichment Analysis Using the Likelihood Ratio Test Statistics Identifies Vascular Endothelial Growth Factor as a Candidate Pathway for Alzheimer's Disease via ITGA5. | 0 |
| 38184221 | 2024 | DPP-4 exacerbates LPS-induced endothelial cells inflammation via integrin-α5β1/FAK/AKT signaling. | 0 |
| 38312030 | 2024 | CircRSU1 alleviates LPS-induced human pulmonary microvascular endothelial cell injury by targeting miR-1224-5p/ITGA5 axis. | 0 |
| 38429832 | 2024 | Integrin α5 regulates motility of human monocyte-derived Langerhans cells during immune response. | 0 |
| 38760287 | 2024 | Relationship between aggressive features of oral squamous cell carcinoma and the immunoexpression of CX3CR1, CX3CL1 and ITGAV. | 0 |
| 38830562 | 2024 | hsa_circ_0000518 stimulates the malignant progression of hepatocellular carcinoma via regulating ITGA5 to activate the Warburg effect. | 0 |
Citation
Dessen P
ITGA5 (integrin subunit alpha 5)
Atlas Genet Cytogenet Oncol Haematol. 2003-08-01
Online version: http://atlasgeneticsoncology.org/gene/41006/itga5
