Identity
HGNC
LOCATION
16p11.2
LOCUSID
ALIAS
CD11A,LFA-1,LFA1A
FUSION GENES
Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 3683
MIM: 153370
HGNC: 6148
Ensembl: ENSG00000005844
Variants:
dbSNP: 3683
ClinVar: 3683
TCGA: ENSG00000005844
COSMIC: ITGAL
RNA/Proteins
Expression (GTEx)
Pathways
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 38195629 | 2024 | LFA-1 nanoclusters integrate TCR stimulation strength to tune T-cell cytotoxic activity. | 0 |
| 38646528 | 2024 | ITGAL expression in non-small-cell lung cancer tissue and its association with immune infiltrates. | 0 |
| 38195629 | 2024 | LFA-1 nanoclusters integrate TCR stimulation strength to tune T-cell cytotoxic activity. | 0 |
| 38646528 | 2024 | ITGAL expression in non-small-cell lung cancer tissue and its association with immune infiltrates. | 0 |
| 37256932 | 2023 | lncRNA PCBP1-AS1 mediated downregulation of ITGAL as a prognostic biomarker in lung adenocarcinoma. | 1 |
| 37256932 | 2023 | lncRNA PCBP1-AS1 mediated downregulation of ITGAL as a prognostic biomarker in lung adenocarcinoma. | 1 |
| 35552271 | 2022 | LFA-1 activation enriches tumor-specific T cells in a cold tumor model and synergizes with CTLA-4 blockade. | 19 |
| 35552271 | 2022 | LFA-1 activation enriches tumor-specific T cells in a cold tumor model and synergizes with CTLA-4 blockade. | 19 |
| 33160625 | 2021 | CD64, CD11a and CD18 leukocytes expression in children with SARS-CoV-2 multisystem inflammatory syndrome versus children with Kawasaki disease: Similar but not the same. | 2 |
| 33160625 | 2021 | CD64, CD11a and CD18 leukocytes expression in children with SARS-CoV-2 multisystem inflammatory syndrome versus children with Kawasaki disease: Similar but not the same. | 2 |
| 30329215 | 2019 | Aggregatibacter actinomycetemcomitans leukotoxin causes activation of lymphocyte function-associated antigen 1. | 12 |
| 30329215 | 2019 | Aggregatibacter actinomycetemcomitans leukotoxin causes activation of lymphocyte function-associated antigen 1. | 12 |
| 30237316 | 2018 | The down-regulation of hsa_circ_0012919, the sponge for miR-125a-3p, contributes to DNA methylation of CD11a and CD70 in CD4(+) T cells of systemic lupus erythematous. | 46 |
| 30237316 | 2018 | The down-regulation of hsa_circ_0012919, the sponge for miR-125a-3p, contributes to DNA methylation of CD11a and CD70 in CD4(+) T cells of systemic lupus erythematous. | 46 |
| 28430662 | 2017 | Histone demethylase JMJD3 regulates CD11a expression through changes in histone H3K27 tri-methylation levels in CD4+ T cells of patients with systemic lupus erythematosus. | 12 |
Citation
Dessen P
ITGAL (integrin subunit alpha L)
Atlas Genet Cytogenet Oncol Haematol. 2003-08-01
Online version: http://atlasgeneticsoncology.org/gene/41013/itgal
