Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 3687
MIM: 151510
HGNC: 6152
Ensembl: ENSG00000140678
Variants:
dbSNP: 3687
ClinVar: 3687
TCGA: ENSG00000140678
COSMIC: ITGAX
RNA/Proteins
| Gene ID | Transcript ID | Uniprot |
|---|---|---|
| ENSG00000140678 | ENST00000268296 | P20702 |
| ENSG00000140678 | ENST00000562522 | H3BN02 |
| ENSG00000140678 | ENST00000562918 | A0A087X131 |
Expression (GTEx)
Pathways
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 36134483 | 2023 | SERPINB8 and furin regulate ITGAX expression and affect the proliferation and invasion of melanoma cells. | 1 |
| 36730754 | 2023 | PAX5/ITGAX Contributed to the Progression of Atherosclerosis by Regulation of B Differentiation via TNF-α Signaling Pathway. | 1 |
| 36134483 | 2023 | SERPINB8 and furin regulate ITGAX expression and affect the proliferation and invasion of melanoma cells. | 1 |
| 36730754 | 2023 | PAX5/ITGAX Contributed to the Progression of Atherosclerosis by Regulation of B Differentiation via TNF-α Signaling Pathway. | 1 |
| 35287505 | 2022 | Identification of ITGAX and CCR1 as potential biomarkers of atherosclerosis via Gene Set Enrichment Analysis. | 4 |
| 35715938 | 2022 | Decreased CD11c-positive dendritic cells in the tumor microenvironment predict double-hit/triple-hit genotype and survival in diffuse large B-cell lymphoma. | 2 |
| 35287505 | 2022 | Identification of ITGAX and CCR1 as potential biomarkers of atherosclerosis via Gene Set Enrichment Analysis. | 4 |
| 35715938 | 2022 | Decreased CD11c-positive dendritic cells in the tumor microenvironment predict double-hit/triple-hit genotype and survival in diffuse large B-cell lymphoma. | 2 |
| 33539617 | 2021 | Dysfunction of complement receptors CR3 (CD11b/18) and CR4 (CD11c/18) in pre-eclampsia: a genetic and functional study. | 8 |
| 34283878 | 2021 | BCR activated CLL B cells use both CR3 (CD11b/CD18) and CR4 (CD11c/CD18) for adhesion while CR4 has a dominant role in migration towards SDF-1. | 1 |
| 33539617 | 2021 | Dysfunction of complement receptors CR3 (CD11b/18) and CR4 (CD11c/18) in pre-eclampsia: a genetic and functional study. | 8 |
| 34283878 | 2021 | BCR activated CLL B cells use both CR3 (CD11b/CD18) and CR4 (CD11c/CD18) for adhesion while CR4 has a dominant role in migration towards SDF-1. | 1 |
| 32824307 | 2020 | Association of Electronegative LDL with Macrophage Foam Cell Formation and CD11c Expression in Rheumatoid Arthritis Patients. | 8 |
| 33032823 | 2020 | High density of stroma-localized CD11c-positive macrophages is associated with longer overall survival in high-grade serous ovarian cancer. | 4 |
| 33055281 | 2020 | An Allosteric Shift in CD11c Affinity Activates a Proatherogenic State in Arrested Intermediate Monocytes. | 6 |
Citation
Dessen P
ITGAX (integrin subunit alpha X)
Atlas Genet Cytogenet Oncol Haematol. 2003-05-01
Online version: http://atlasgeneticsoncology.org/gene/41016/itgax
