Identity
HGNC
LOCATION
10p11.22
LOCUSID
ALIAS
CD29,FNRB,GPIIA,MDF2,MSK12,VLA-BETA,VLAB
FUSION GENES
Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 3688
MIM: 135630
HGNC: 6153
Ensembl: ENSG00000150093
Variants:
dbSNP: 3688
ClinVar: 3688
TCGA: ENSG00000150093
COSMIC: ITGB1
RNA/Proteins
Expression (GTEx)
Pathways
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 37945815 | 2024 | microRNA-205 represses breast cancer metastasis by perturbing the rab coupling protein [RCP]-mediated integrin β1 recycling on the membrane. | 0 |
| 38184221 | 2024 | DPP-4 exacerbates LPS-induced endothelial cells inflammation via integrin-α5β1/FAK/AKT signaling. | 0 |
| 38254031 | 2024 | Cancer-associated fibroblast-derived extracellular vesicles promote lymph node metastases in oral cavity squamous cell carcinoma by encapsulating ITGB1 and BMI1. | 0 |
| 38279122 | 2024 | Integrinβ-1 in disorders and cancers: molecular mechanisms and therapeutic targets. | 2 |
| 38295227 | 2024 | Osteosarcoma Cells Secrete CXCL14 That Activates Integrin α11β1 on Fibroblasts to Form a Lung Metastatic Niche. | 0 |
| 38367240 | 2024 | Suppression of the METTL3-m(6)A-integrin β1 axis by extracellular acidification impairs T cell infiltration and antitumor activity. | 0 |
| 38490094 | 2024 | N-linked α2,6-sialylation of integrin β1 by the sialyltransferase ST6Gal1 promotes cell proliferation and stemness in gestational trophoblastic disease. | 0 |
| 38498701 | 2024 | Interactions between integrin α9β1 and VCAM-1 promote neutrophil hyperactivation and mediate poststroke DVT. | 0 |
| 38511888 | 2024 | CD93 regulates breast cancer growth and vasculogenic mimicry through the PI3K/AKT/SP2 signaling pathway activated by integrin β1. | 0 |
| 38532364 | 2024 | A decrease in integrin α5β1/FAK is associated with increased apoptosis of aortic smooth muscle cells in acute type a aortic dissection. | 0 |
| 38622980 | 2024 | IGSF10 inhibits the metastasis of lung adenocarcinoma via the Spi-B/Integrin-β1 signaling pathway. | 0 |
| 38678170 | 2024 | Semaphorin 7A promotes endothelial permeability and inflammation via plexin C1 and integrin β1 in Kawasaki disease. | 0 |
| 38775153 | 2024 | Blocking the angiopoietin-2-dependent integrin β-1 signaling axis abrogates small cell lung cancer invasion and metastasis. | 0 |
| 38892056 | 2024 | ADAM12-Generated Basigin Ectodomain Binds β1 Integrin and Enhances the Expression of Cancer-Related Extracellular Matrix Proteins. | 0 |
| 37945815 | 2024 | microRNA-205 represses breast cancer metastasis by perturbing the rab coupling protein [RCP]-mediated integrin β1 recycling on the membrane. | 0 |
Citation
Dessen P
ITGB1 (integrin subunit beta 1)
Atlas Genet Cytogenet Oncol Haematol. 2003-06-01
Online version: http://atlasgeneticsoncology.org/gene/41017/itgb1
