ITGB1BP1 (integrin subunit beta 1 binding protein 1)

2007-04-01  

Identity

HGNC
LOCATION
2p25.1
LOCUSID
ALIAS
ICAP-1A,ICAP-1B,ICAP-1alpha,ICAP1,ICAP1A,ICAP1B
FUSION GENES

Other Information

Locus ID:

NCBI: 9270
MIM: 607153
HGNC: 23927
Ensembl: ENSG00000119185

Variants:

dbSNP: 9270
ClinVar: 9270
TCGA: ENSG00000119185
COSMIC: ITGB1BP1

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000119185ENST00000238091O14713
ENSG00000119185ENST00000355346O14713
ENSG00000119185ENST00000359712A8MPU2
ENSG00000119185ENST00000360635O14713
ENSG00000119185ENST00000456913A8MPU2
ENSG00000119185ENST00000460001C9J6Y2
ENSG00000119185ENST00000464228F8WF20
ENSG00000119185ENST00000467606C9JZ07
ENSG00000119185ENST00000483795G3V1A3
ENSG00000119185ENST00000484735C9J0J6
ENSG00000119185ENST00000488451O14713
ENSG00000119185ENST00000492079C9JBU8
ENSG00000119185ENST00000494563C9J5T5
ENSG00000119185ENST00000497105C9IZZ8

Expression (GTEx)

0
10
20
30
40
50
60
70
80
90

References

Pubmed IDYearTitleCitations
320056692020Serine phosphorylation of the small phosphoprotein ICAP1 inhibits its nuclear accumulation.5
320056692020Serine phosphorylation of the small phosphoprotein ICAP1 inhibits its nuclear accumulation.5
280033632017Nuclear Localization of Integrin Cytoplasmic Domain-associated Protein-1 (ICAP1) Influences β1 Integrin Activation and Recruits Krev/Interaction Trapped-1 (KRIT1) to the Nucleus.16
280497202017ICAP-1 monoubiquitylation coordinates matrix density and rigidity sensing for cell migration through ROCK2-MRCKα balance.4
280033632017Nuclear Localization of Integrin Cytoplasmic Domain-associated Protein-1 (ICAP1) Influences β1 Integrin Activation and Recruits Krev/Interaction Trapped-1 (KRIT1) to the Nucleus.16
280497202017ICAP-1 monoubiquitylation coordinates matrix density and rigidity sensing for cell migration through ROCK2-MRCKα balance.4
233175062013Mechanism for KRIT1 release of ICAP1-mediated suppression of integrin activation.57
236955612013Cocrystal structure of the ICAP1 PTB domain in complex with a KRIT1 peptide.7
233175062013Mechanism for KRIT1 release of ICAP1-mediated suppression of integrin activation.57
236955612013Cocrystal structure of the ICAP1 PTB domain in complex with a KRIT1 peptide.7
227363992012Annexin A1 is associated with gastric cancer survival and promotes gastric cancer cell invasiveness through the formyl peptide receptor/extracellular signal-regulated kinase/integrin beta-1-binding protein 1 pathway.47
227363992012Annexin A1 is associated with gastric cancer survival and promotes gastric cancer cell invasiveness through the formyl peptide receptor/extracellular signal-regulated kinase/integrin beta-1-binding protein 1 pathway.47
206163132010Integrin cytoplasmic domain-associated protein-1 attenuates sprouting angiogenesis.36
206163132010Integrin cytoplasmic domain-associated protein-1 attenuates sprouting angiogenesis.36
191245062009Common genetic variation in candidate genes and susceptibility to subtypes of breast cancer.27

Citation

Dessen P

ITGB1BP1 (integrin subunit beta 1 binding protein 1)

Atlas Genet Cytogenet Oncol Haematol. 2007-04-01

Online version: http://atlasgeneticsoncology.org/gene/47086/itgb1bp1