Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 3691
MIM: 147557
HGNC: 6158
Ensembl: ENSG00000132470
Variants:
dbSNP: 3691
ClinVar: 3691
TCGA: ENSG00000132470
COSMIC: ITGB4
RNA/Proteins
Expression (GTEx)
Pathways
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 37160555 | 2024 | Exosome-transmitted FOSL1 from cancer-associated fibroblasts drives colorectal cancer stemness and chemo-resistance through transcriptionally activating ITGB4. | 4 |
| 38071887 | 2024 | Unraveling dedifferentiation and metastasis traces in pancreatic ductal adenocarcinoma ductal cells: Insights from single-cell RNA sequencing analysis of ITGB4 and C19orf33. | 1 |
| 38131229 | 2024 | Identification of ITGB4 as a novel tumor promoting gene in lung adenocarcinoma (LUAD). | 0 |
| 38172503 | 2024 | ITGB4 upregulation is associated with progression of lower grade glioma. | 0 |
| 38281617 | 2024 | ING3 inhibits the malignant progression of lung adenocarcinoma by negatively regulating ITGB4 expression to inactivate Src/FAK signaling. | 0 |
| 38375821 | 2024 | MDFI promotes the proliferation and tolerance to chemotherapy of colorectal cancer cells by binding ITGB4/LAMB3 to activate the AKT signaling pathway. | 1 |
| 38831335 | 2024 | NEDD4L mediates ITGB4 ubiquitination and degradation to suppress esophageal carcinoma progression. | 0 |
| 37160555 | 2024 | Exosome-transmitted FOSL1 from cancer-associated fibroblasts drives colorectal cancer stemness and chemo-resistance through transcriptionally activating ITGB4. | 4 |
| 38071887 | 2024 | Unraveling dedifferentiation and metastasis traces in pancreatic ductal adenocarcinoma ductal cells: Insights from single-cell RNA sequencing analysis of ITGB4 and C19orf33. | 1 |
| 38131229 | 2024 | Identification of ITGB4 as a novel tumor promoting gene in lung adenocarcinoma (LUAD). | 0 |
| 38172503 | 2024 | ITGB4 upregulation is associated with progression of lower grade glioma. | 0 |
| 38281617 | 2024 | ING3 inhibits the malignant progression of lung adenocarcinoma by negatively regulating ITGB4 expression to inactivate Src/FAK signaling. | 0 |
| 38375821 | 2024 | MDFI promotes the proliferation and tolerance to chemotherapy of colorectal cancer cells by binding ITGB4/LAMB3 to activate the AKT signaling pathway. | 1 |
| 38831335 | 2024 | NEDD4L mediates ITGB4 ubiquitination and degradation to suppress esophageal carcinoma progression. | 0 |
| 35112314 | 2023 | Revising the Role of Integrin Subunit β4 Expression in Colon Cancer Progression and Survival. | 0 |
Citation
Dessen P
ITGB4 (integrin subunit beta 4)
Atlas Genet Cytogenet Oncol Haematol. 2003-02-01
Online version: http://atlasgeneticsoncology.org/gene/41020/itgb4
