JADE1 (jade family PHD finger 1)

2007-02-01  

Identity

HGNC
LOCATION
4q28.2
LOCUSID
ALIAS
PHF17
FUSION GENES

Other Information

Locus ID:

NCBI: 79960
MIM: 610514
HGNC: 30027
Ensembl: ENSG00000077684

Variants:

dbSNP: 79960
ClinVar: 79960
TCGA: ENSG00000077684
COSMIC: JADE1

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000077684ENST00000226319Q6IE81
ENSG00000077684ENST00000413543Q6IE81
ENSG00000077684ENST00000452328Q6IE81
ENSG00000077684ENST00000503785D6RC05
ENSG00000077684ENST00000504089D6RFK0
ENSG00000077684ENST00000507833D6RBB3
ENSG00000077684ENST00000508997D6RCS1
ENSG00000077684ENST00000510308D6RGE7
ENSG00000077684ENST00000511647Q6IE81
ENSG00000077684ENST00000511925D6RAS5
ENSG00000077684ENST00000512960Q6IE81
ENSG00000077684ENST00000514740D6RE74
ENSG00000077684ENST00000610919Q6IE81
ENSG00000077684ENST00000611140Q6IE81

Expression (GTEx)

0
5
10
15
20
25
30
35
40

Pathways

PathwaySourceExternal ID
Chromatin organizationREACTOMER-HSA-4839726
Chromatin modifying enzymesREACTOMER-HSA-3247509
HATs acetylate histonesREACTOMER-HSA-3214847

Protein levels (Protein atlas)

Not detected
Low
Medium
High

References

Pubmed IDYearTitleCitations
188067872008Jade-1 inhibits Wnt signalling by ubiquitylating beta-catenin and mediates Wnt pathway inhibition by pVHL.80
240970612013A novel non-coding RNA lncRNA-JADE connects DNA damage signalling to histone H4 acetylation.41
121696912002The von Hippel-Lindau tumor suppressor stabilizes novel plant homeodomain protein Jade-1.33
186847142008Role of Jade-1 in the histone acetyltransferase (HAT) HBO1 complex.27
226541122012The ciliary protein nephrocystin-4 translocates the canonical Wnt regulator Jade-1 to the nucleus to negatively regulate β-catenin signaling.24
160465452005Jade-1, a candidate renal tumor suppressor that promotes apoptosis.23
155021582004von Hippel-Lindau partner Jade-1 is a transcriptional co-activator associated with histone acetyltransferase activity.21
271604562016Novel Genetic Loci Associated with the Plasma Triglyceride Response to an Omega-3 Fatty Acid Supplementation.9
247395122014Cell cycle-dependent chromatin shuttling of HBO1-JADE1 histone acetyl transferase (HAT) complex.8
251007262014Casein kinase 1 α phosphorylates the Wnt regulator Jade-1 and modulates its activity.8

Citation

Dessen P

JADE1 (jade family PHD finger 1)

Atlas Genet Cytogenet Oncol Haematol. 2007-02-01

Online version: http://atlasgeneticsoncology.org/gene/43934/jade1