JCAD (junctional cadherin 5 associated)

2017-10-01  

Identity

HGNC
LOCATION
10p11.23
LOCUSID
ALIAS
KIAA1462

Other Information

Locus ID:

NCBI: 57608
MIM: 614398
HGNC: 29283
Ensembl: ENSG00000165757

Variants:

dbSNP: 57608
ClinVar: 57608
TCGA: ENSG00000165757
COSMIC: JCAD

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000165757ENST00000375377Q9P266

Protein levels (Protein atlas)

Not detected
Low
Medium
High

References

Pubmed IDYearTitleCitations
192047262009Transcriptomic and genetic studies identify IL-33 as a candidate gene for Alzheimer's disease.63
210880112011Genome-wide association study identifies a new locus for coronary artery disease on chromosome 10p11.23.41
210880112011Genome-wide association study identifies a new locus for coronary artery disease on chromosome 10p11.23.41
287751682017JCAD Promotes Progression of Nonalcoholic Steatohepatitis to Liver Cancer by Inhibiting LATS2 Kinase Activity.10
287057942017Targeted Disruption of JCAD (Junctional Protein Associated With Coronary Artery Disease)/KIAA1462, a Coronary Artery Disease-Associated Gene Product, Inhibits Angiogenic Processes In Vitro and In Vivo.7
297941142018JCAD, a Gene at the 10p11 Coronary Artery Disease Locus, Regulates Hippo Signaling in Endothelial Cells.7
243492192013KIAA1462, a coronary artery disease associated gene, is a candidate gene for late onset Alzheimer disease in APOE carriers.6

Citation

Dessen P

JCAD (junctional cadherin 5 associated)

Atlas Genet Cytogenet Oncol Haematol. 2017-10-01

Online version: http://atlasgeneticsoncology.org/gene/57115/jcad